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Fig. 4 | BMC Cancer

Fig. 4

From: 4’-O-Methylbroussochalcone B as a novel tubulin polymerization inhibitor suppressed the proliferation and migration of acute myeloid leukaemia cells

Fig. 4

4′-O-Methylbroussochalcone B induced apoptosis and regulated apoptosis-related proteins in ML-2 cells and OCI-AML5 cells. a-b Measurement of apoptosis in ML-2 cells and OCI-AML5 cells using flow cytometry analysis; c Western Blot analyzed the expression level of Cleaved-caspase 3/9, cleaved-parp, Bcl-2, Bax and XIAP in ML-2 cells, full-length blots/gels are presented in Supplementary Fig. S3A; d Western Blot analyzed the expression level of Cleaved-caspase 3/9, cleaved-parp, Bcl-2, Bax and XIAP in OCI-AML5 cells, full-length blots/gels are presented in Supplementary Fig. S3b.The data were presented as the mean ± SEM *P < 0.05, **P < 0.01, ***P < 0.001 and ****P < 0.0001 vs the control

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BMC Cancer

ISSN: 1471-2407

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