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Fig. 3 | BMC Cancer

Fig. 3

From: 4’-O-Methylbroussochalcone B as a novel tubulin polymerization inhibitor suppressed the proliferation and migration of acute myeloid leukaemia cells

Fig. 3

4′-O-Methylbroussochalcone B inhibited G2-M phase and migration in ML-2 cells and OCI-AML5 cells. a-b Cell cycle assay for ML-2 cells and OCI-AML5 cells at different concentrations of 4′-O-Methylbroussochalcone; c Transwell assay for ML-2 cells and OCI-AML5 cells at different concentrations of 4′-O-Methylbroussochalcone; d Western Blot measured the expression level of N-cadherin, Vimentin, E-cadherin, Snail-1, and Slug in ML-2 cells, full-length blots/gels are presented in Supplementary Fig. S2B; e Western Blot measured the expression level of N-cadherin, Vimentin, E-cadherin, Snail-1, and Slug in OCI-AML5 cells, full-length blots/gels are presented in Supplementary Fig. S2C. The data were presented as the mean ± SEM *P < 0.05, **P < 0.01, ***P < 0.001 and ****P < 0.0001, vs the control

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