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Table 4 The 5-year and 8-year overall survival rates, event free survival rates, cumulated incidence of relapse and 2-year therapy-related mortality for each groups

From: Reduced intensity of early intensification does not increase the risk of relapse in children with standard risk acute lymphoblastic leukemia - a multi-centric clinical study of GD-2008-ALL protocol

 

SR groups

IR groups

HR groups

p

5-year OS (%)

90.7±1.4

86.0±1.2

68.5±2.5

< 0.01

8-year OS (%)

89.6±1.6

85.8±1.3

68.5±2.5

< 0.01

5-year EFS (%)

83.1±1.8

77.6±1.5

61.6±2.6

< 0.01

8-year EFS (%)

81.6±2.0

76.3±1.6

61.6±2.6

< 0.01

5-year CIR (%)

15.1±1.8

19.1±1.5

26.7±2.5

< 0.01

8-year CIR (%)

16.4±1.9

20.1±1.5

26.7±2.5

< 0.01

2-yearTRM (%)

1.7±0.6

3.9±0.7

12.7±1.8

< 0.01

  1. Abbreviations: OS overall survival, EFS event free survival, CIR cumulated incidence of relapse, TRM therapy related mortality, SR standard risk, IR intermediate risk, HR high risk