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Table 4 Overall analysis of miR-34a expression association with clinicopathologic characteristics

From: Prognostic value of low microRNA-34a expression in human gastrointestinal cancer: a systematic review and meta-analysis

Clinicopathological characteristics

Num. of studies

Num. of patients

Pooled OR (95%CI)

Heterogeneity

Fixed

Random

I2

p-value

Gender (male vs. female)

7

647

0.776 (0.566–1.065)

0.777 (0.565–1.067)

0.0%

0.888

Tumor Size (≤5 vs > 5 cm)

3

326

0.736 (0.460–1.177)

0.284 (0.433–1.288)

20.5%

0.284

Lymphatic Metastasis (YESvs.NO)

6

571

3.231 (2.237–4.666)

3.200 (2.210–4.635)

0.0%

0.754

TNM stage (III + IV vs. I + II)

5

458

2.468 (1.698–3.588)

2.896 (1.302–6.442)

74.4%

0.004

Differentiation (poor vs. others)

6

597

2.228 (1.538–3.228)

2.373 (1.430–3.938)

35.7%

0.169

  1. Abbreviations: 95%CI 95% confidence interval, Fixed, fixed effects model, OR Odds ratio, Random, random pooling model