Table 5 Analysis of high-risk factors in lung cancer stratified by gender
From: Current lung cancer screening guidelines may miss high-risk population: a real-world study
Characteristic | Male | Female | ||||
|---|---|---|---|---|---|---|
Patients with | Patients without | P value | Patients with | Patients without | P value | |
lung cancer, n(%) | lung cancer, n(%) | lung cancer, n(%) | lung cancer, n(%) | |||
Total | 73 (0.7) | 9728 (99.3) | Â | 69 (1.1) | 6126 (98.9) | 0.021 b |
Age (years) a | 62.10 ± 13.51 | 51.18 ± 14.74 | < 0.0001 | 59.17 ± 13.44 | 48.69 ± 14.73 | < 0.0001 |
< 30 | 0 (0) | 545 (5.6) |  | 0 (0) | 586 (9.6) |  |
30~ | 0 (0) | 627 (6.4) | Â | 0 (0) | 397 (6.5) | Â |
35~ | 2 (2.7) | 732 (7.5) | Â | 1 (1.4) | 474 (7.7) | Â |
40~ | 6 (8.2) | 1497 (15.4) | Â | 8 (11.6) | 1158 (18.9) | Â |
45~ | 9 (12.3) | 1607 (16.5) | Â | 14 (20.3) | 1044 (17.0) | Â |
50~ | 8 (11.0) | 1288 (13.2) | Â | 10 (14.5) | 710 (11.6) | Â |
55~ | 4 (5.5) | 1063 (10.9) | Â | 4 (5.8) | 472 (7.7) | Â |
60~ | 7 (9.6) | 591 (6.1) | Â | 6 (8.7) | 363 (5.9) | Â |
65~ | 13 (17.8) | 422 (4.3) | Â | 5 (7.2) | 231 (3.7) | Â |
70~ | 7 (9.6) | 446 (4.6) | Â | 8 (11.6) | 192 (3.1) | Â |
75~ | 9 (12.3) | 370 (3.8) | Â | 6 (8.7) | 269 (4.4) | Â |
80~ | 8 (11.0) | 540 (5.6) | Â | 7 (10.1) | 230 (3.8) | Â |
Smoking history | 55 (75.3) | 5299 (54.5) | 0.000 | 4 (5.8) | 52 (0.8) | 0.003 |
Chronic obstructive pulmonary disease | 24 (32.9) | 1821 (18.7) | 0.002 | 9 (13.0) | 606 (9.9) | 0.384 |
Diffuse pulmonary fibrosis | 17 (23.3) | 1440 (14.8) | 0.042 | 6 (8.7) | 732 (11.9) | 0.407 |
Previous pulmonary tuberculosis | 4 (5.5) | 357 (3.7) | 0.346 | 1 (1.4) | 168 (2.7) | 1.000 |
Previous history of malignant tumor | 11 (15.1) | 268 (2.8) | < 0.0001 | 12 (17.4) | 691 (11.3) | 0.112 |
Family history of cancer | 5 (6.8) | 723 (7.4) | 0.850 | 10 (14.5) | 751 (12.3) | 0.574 |
Number of first-degree relatives with cancer | 5 (6.8) | 653 (6.7) | 0.371 | 10 (14.5) | 655 (10.7) | 0.478 |
Family history of lung cancer | 2 (2.7) | 185 (1.9) | 0.651 | 1 (1.4) | 213 (3.5) | 0.733 |
Number of first-degree relatives with lung cancer | 1 (1.4) | 162 (1.7) | 0.287 | 1 (1.4) | 180 (2.9) | 0.888 |