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Table 5 Analysis of high-risk factors in lung cancer stratified by gender

From: Current lung cancer screening guidelines may miss high-risk population: a real-world study

Characteristic Male Female
Patients with Patients without P value Patients with Patients without P value
lung cancer, n(%) lung cancer, n(%) lung cancer, n(%) lung cancer, n(%)
Total 73 (0.7) 9728 (99.3)   69 (1.1) 6126 (98.9) 0.021 b
Age (years) a 62.10 ± 13.51 51.18 ± 14.74 < 0.0001 59.17 ± 13.44 48.69 ± 14.73 < 0.0001
< 30 0 (0) 545 (5.6)   0 (0) 586 (9.6)  
30~ 0 (0) 627 (6.4)   0 (0) 397 (6.5)  
35~ 2 (2.7) 732 (7.5)   1 (1.4) 474 (7.7)  
40~ 6 (8.2) 1497 (15.4)   8 (11.6) 1158 (18.9)  
45~ 9 (12.3) 1607 (16.5)   14 (20.3) 1044 (17.0)  
50~ 8 (11.0) 1288 (13.2)   10 (14.5) 710 (11.6)  
55~ 4 (5.5) 1063 (10.9)   4 (5.8) 472 (7.7)  
60~ 7 (9.6) 591 (6.1)   6 (8.7) 363 (5.9)  
65~ 13 (17.8) 422 (4.3)   5 (7.2) 231 (3.7)  
70~ 7 (9.6) 446 (4.6)   8 (11.6) 192 (3.1)  
75~ 9 (12.3) 370 (3.8)   6 (8.7) 269 (4.4)  
80~ 8 (11.0) 540 (5.6)   7 (10.1) 230 (3.8)  
Smoking history 55 (75.3) 5299 (54.5) 0.000 4 (5.8) 52 (0.8) 0.003
Chronic obstructive pulmonary disease 24 (32.9) 1821 (18.7) 0.002 9 (13.0) 606 (9.9) 0.384
Diffuse pulmonary fibrosis 17 (23.3) 1440 (14.8) 0.042 6 (8.7) 732 (11.9) 0.407
Previous pulmonary tuberculosis 4 (5.5) 357 (3.7) 0.346 1 (1.4) 168 (2.7) 1.000
Previous history of malignant tumor 11 (15.1) 268 (2.8) < 0.0001 12 (17.4) 691 (11.3) 0.112
Family history of cancer 5 (6.8) 723 (7.4) 0.850 10 (14.5) 751 (12.3) 0.574
Number of first-degree relatives with cancer 5 (6.8) 653 (6.7) 0.371 10 (14.5) 655 (10.7) 0.478
Family history of lung cancer 2 (2.7) 185 (1.9) 0.651 1 (1.4) 213 (3.5) 0.733
Number of first-degree relatives with lung cancer 1 (1.4) 162 (1.7) 0.287 1 (1.4) 180 (2.9) 0.888
  1. aValues are reported as mean ± SD (range). bThe detection rate of lung cancer in women is compared with that in men.