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Table 2 Univariate and multivariate Cox proportional hazards regression models for progression free survival

From: Secondary endpoints analysis in patients with estrogen receptor-positive metastatic breast cancer treated with everolimus and exemestane enrolled in Oral Care-BC

 

Univariate

Multivariate

HR (95% CI)

P-value

HR (95% CI)

P-value

D Group, B Group

0.97 (0.64, 1.46)

0.879

1.11 (0.72, 1.72)

0.628

Age (≥ 65, < 65 years)

0.97 (0.64, 1.46)

0.874

1.04 (0.66, 1.66)

0.862

Use of BMA, No use

1.26 (0.84, 1.89)

0.255

1.71 (1.06, 2.77)

0.028

Chemotherapy, No use

1.03 (0.55, 1.93)

0.930

1.19 (0.60, 2.37)

0.618

BMI ≥ 25, < 25

1.85 (1.16, 2.96)

0.010

1.84 (1.11, 3.04)

0.018

PgR+, −

1.02 (0.60, 1.72)

0.952

0.70 (0.38, 1.29)

0.257

Visceral, No visceral

1.98 (1.27, 3.08)

0.002

2.13 (1.31, 3.49)

0.003

Metastatic, De novo

1.05 (0.65, 1.69)

0.855

0.87 (0.49, 1.54)

0.625

Endocrine therapy 2, 0–1

1.34 (0.80, 2.22)

0.265

1.13 (0.60, 2.13)

0.701

Endocrine therapy 3, 0–1

1.22 (0.76, 1.96)

0.409

0.95 (0.56, 1.62)

0.856

Incidence of oral mucositis within 8 weeks, None

1.19 (0.69, 2.04)

0.536

1.41 (0.78, 2.57)

0.260