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Fig. 5 | BMC Cancer

Fig. 5

From: The oncometabolite R-2-hydroxyglutarate dysregulates the differentiation of human mesenchymal stromal cells via inducing DNA hypermethylation

Fig. 5

R-2HG induced DNA hypermethylation during mesenchymal stromal cells (MSCs) differentiation. a. Stacking bar graph showing percentages of hyper and hypo methylated CpG sites of R-2HG vs. Control MSCs during osteogenic differentiation. b. Methylation of lineage-specific genes during osteogenic differentiation. c. Percentages of hyper and hypo methylated CpG sites of R-2HG treated MSCs vs. Control MSCs during chondrogenic differentiation. d. Methylation of lineage-specific genes during chondrogenic differentiation

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BMC Cancer

ISSN: 1471-2407

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