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Fig. 4 | BMC Cancer

Fig. 4

From: The oncometabolite R-2-hydroxyglutarate dysregulates the differentiation of human mesenchymal stromal cells via inducing DNA hypermethylation

Fig. 4

R-2HG induced DNA hypermethylation states of mesenchymal stromal cells (MSCs) in the proliferating condition. a: Heatmap displays 154 genes with significant differences in the expression levels between MSCs in the absence or presence of R-2HG (1 mM). b: Distribution pattern of DNA methylation. c: Results of ingenuity pathway analysis (IPA)

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