Fig. 3

Adipogenic differentiation of mesenchymal stromal cells (MSCs) in the presence of R-2HG. a. MSCs were grown in adipogenic differentiation medium for 21 days in the absence or presence of R-2HG (1, 1.5 mM). Lipid vacuoles were assessed by oil red O staining. Scale bar = 100 μM (b): Quantitative results of the expression levels of differentiation-related genes. * P < 0.05 vs. the group of MSCs in absence of R-2HG. ** P < 0.01 vs. the group of MSCs in absence of R-2HG