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Table 2 Effect of NPPN on immune function in mice with immunosuppression caused by CTX (\( \overline{x}\pm s \), n = 10)

From: Neutral polysaccharide from Panax notoginseng enhanced cyclophosphamide antitumor efficacy in hepatoma H22-bearing mice

Group

Dosage

(mg·kg−1)

Thymus index

Spleen index

Stimulation index

Absorbance value of serum hemolysin

NK cell activity (%)

κ

α

Normal

–

3.80 ± 0.80**

3.05 ± 0.68**

1.07 ± 0.05**

0.59 ± 0.01**

62.16 ± 4.59**

0.023 ± 0.007*

5.12 ± 0.37**

CTX

80

0.68 ± 0.08

1.17 ± 0.13

0.91 ± 0.05

0.36 ± 0.04

25.42 ± 8.33

0.017 ± 0.004

4.69 ± 0.25

NPPN-L + CTX

93 + 80

0.76 ± 0.09

1.33 ± 0.29

0.96 ± 0.04**

0.55 ± 0.05**

35.56 ± 6.47**

0.024 ± 0.006*

4.94 ± 0.47

NPPN-M + CTX

188 + 80

0.86 ± 0.12

1.22 ± 0.27

0.97 ± 0.05**

0.57 ± 0.03**

29.07 ± 5.27

0.022 ± 0.004

4.77 ± 0.40

NPPN-H + CTX

375 + 80

0.98 ± 0.06*

1.29 ± 0.17

0.94 ± 0.01

0.57 ± 0.03**

35.13 ± 5.93**

0.025 ± 0.005**

5.10 ± 0.28**

  1. Notes: * P < 0.05, ** P < 0.01 vs. CTX