TY - JOUR AU - Mendenhall, W. M. AU - Zlotecki, R. A. AU - Scarborough, M. T. AU - Gibbs, C. P. AU - Mendenhall, N. P. PY - 2006 DA - 2006// TI - Giant cell tumor of bone JO - Am J Clin Oncol VL - 29 UR - https://doi.org/10.1097/01.coc.0000195089.11620.b7 DO - 10.1097/01.coc.0000195089.11620.b7 ID - Mendenhall2006 ER - TY - JOUR AU - Alberghini, M. AU - Kliskey, K. AU - Krenacs, T. AU - Picci, P. AU - Kindblom, L. AU - Forsyth, R. PY - 2010 DA - 2010// TI - Morphological and immunophenotypic features of primary and metastatic giant cell tumour of bone JO - Virchows Arch VL - 456 UR - https://doi.org/10.1007/s00428-009-0863-2 DO - 10.1007/s00428-009-0863-2 ID - Alberghini2010 ER - TY - STD TI - NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Bone Cancer. Version 1. 2018. https://www.nccn.org/professionals/physician_gls/PDF/bone.pdf. UR - https://www.nccn.org/professionals/physician_gls/PDF/bone.pdf ID - ref3 ER - TY - CHAP AU - Flanagan, A. AU - Larousserie, F. AU - O’Donnel, P. PY - 2020 DA - 2020// TI - Giant cell tumor of bone BT - WHO classification of tumours PB - International Agency for Research on Cancer CY - Lyon ID - Flanagan2020 ER - TY - JOUR AU - Palmerini, E. AU - Picci, P. AU - Reichardt, P. AU - Downey, G. PY - 2019 DA - 2019// TI - Malignancy in giant cell tumor of bone: a review of the literature JO - Technol Cancer Res Treat VL - 18 UR - https://doi.org/10.1177/1533033819840000 DO - 10.1177/1533033819840000 ID - Palmerini2019 ER - TY - JOUR AU - Gong, L. AU - Liu, W. AU - Sun, X. AU - Sajdik, C. AU - Tian, X. AU - Niu, X. PY - 2012 DA - 2012// TI - Histological and clinical characteristics of malignant giant cell tumor of bone JO - Virchows Arch VL - 460 UR - https://doi.org/10.1007/s00428-012-1198-y DO - 10.1007/s00428-012-1198-y ID - Gong2012 ER - TY - JOUR AU - Bertoni, F. AU - Bacchini, P. AU - Staals, E. L. PY - 2003 DA - 2003// TI - Malignancy in giant cell tumor of bone JO - Cancer. VL - 97 UR - https://doi.org/10.1002/cncr.11359 DO - 10.1002/cncr.11359 ID - Bertoni2003 ER - TY - JOUR AU - Rock, M. G. AU - Sim, F. H. AU - Unni, K. K. AU - Witrak, G. A. AU - Frassica, F. J. AU - Schray, M. F. PY - 1986 DA - 1986// TI - Secondary malignant giant-cell tumor of bone. Clinicopathological assessment of nineteen patients JO - J Bone Joint Surg Am VL - 68 UR - https://doi.org/10.2106/00004623-198668070-00016 DO - 10.2106/00004623-198668070-00016 ID - Rock1986 ER - TY - JOUR AU - Unni, K. K. PY - 2001 DA - 2001// TI - How to diagnose malignant giant cell tumor JO - AJSP: Rev Rep VL - 6 ID - Unni2001 ER - TY - STD TI - XGEVA®. In: Denosumab prescribing information. Thousand Oaks: Amgen Inc.; 2020. ID - ref10 ER - TY - JOUR AU - Chawla, S. AU - Blay, J. Y. AU - Rutkowski, P. AU - Cesne, A. AU - Reichardt, P. AU - Gelderblom, H. PY - 2019 DA - 2019// TI - Denosumab in patients with giant-cell tumour of bone: a multicentre, open-label, phase 2 study JO - Lancet Oncol. VL - 20 UR - https://doi.org/10.1016/S1470-2045(19)30663-1 DO - 10.1016/S1470-2045(19)30663-1 ID - Chawla2019 ER - TY - JOUR AU - Mondal, A. AU - Kundu, B. AU - Gupta, S. AU - Biswas, J. PY - 2002 DA - 2002// TI - Secondary malignant giant cell tumour of bone--a study of five cases with short review of literature JO - Indian J Pathol Microbiol VL - 45 ID - Mondal2002 ER - TY - JOUR AU - Boriani, S. AU - Sudanese, A. AU - Baldini, N. AU - Picci, P. PY - 1986 DA - 1986// TI - Sarcomatous degeneration of giant cell tumours JO - Ital J Orthop Traumatol VL - 12 ID - Boriani1986 ER - TY - JOUR AU - Campanacci, M. AU - Baldini, N. AU - Boriani, S. AU - Sudanese, A. PY - 1987 DA - 1987// TI - Giant-cell tumor of bone JO - J Bone Joint Surg Am VL - 69 UR - https://doi.org/10.2106/00004623-198769010-00018 DO - 10.2106/00004623-198769010-00018 ID - Campanacci1987 ER - TY - JOUR AU - Domovitov, S. V. AU - Healey, J. H. PY - 2010 DA - 2010// TI - Primary malignant giant-cell tumor of bone has high survival rate JO - Ann Surg Oncol VL - 17 UR - https://doi.org/10.1245/s10434-009-0803-z DO - 10.1245/s10434-009-0803-z ID - Domovitov2010 ER - TY - JOUR AU - Anract, P. AU - Pinieux, G. AU - Cottias, P. AU - Pouillart, P. AU - Forest, M. AU - Tomeno, B. PY - 1998 DA - 1998// TI - Malignant giant-cell tumours of bone. Clinico-pathological types and prognosis: a review of 29 cases JO - Int Orthop VL - 22 UR - https://doi.org/10.1007/s002640050201 DO - 10.1007/s002640050201 ID - Anract1998 ER - TY - BOOK AU - Unni, K. K. AU - Inwards, C. Y. PY - 2010 DA - 2010// TI - Dahlin’s bone tumours: general aspects and data on 10165 cases PB - Wilkins CY - Philadelphia ID - Unni2010 ER - TY - JOUR AU - Skubitz, K. M. PY - 2014 DA - 2014// TI - Giant cell tumor of bone: current treatment options JO - Curr Treat Options in Oncol VL - 15 UR - https://doi.org/10.1007/s11864-014-0289-1 DO - 10.1007/s11864-014-0289-1 ID - Skubitz2014 ER - TY - JOUR AU - Healey, J. H. PY - 2019 DA - 2019// TI - Denosumab for giant cell tumour of bone: success and limitations JO - Lancet Oncol. VL - 20 UR - https://doi.org/10.1016/S1470-2045(19)30660-6 DO - 10.1016/S1470-2045(19)30660-6 ID - Healey2019 ER - TY - JOUR AU - Engellau, J. AU - Seeger, L. AU - Grimer, R. AU - Henshaw, R. AU - Gelderblom, H. AU - Choy, E. PY - 2018 DA - 2018// TI - Assessment of denosumab treatment effects and imaging response in patients with giant cell tumor of bone JO - World J Surg Oncol VL - 16 UR - https://doi.org/10.1186/s12957-018-1478-3 DO - 10.1186/s12957-018-1478-3 ID - Engellau2018 ER - TY - JOUR AU - Ueda, T. AU - Morioka, H. AU - Nishida, Y. AU - Kakunaga, S. AU - Tsuchiya, H. AU - Matsumoto, Y. PY - 2015 DA - 2015// TI - Objective tumor response to denosumab in patients with giant cell tumor of bone: a multicenter phase II trial JO - Ann Oncol VL - 26 UR - https://doi.org/10.1093/annonc/mdv307 DO - 10.1093/annonc/mdv307 ID - Ueda2015 ER - TY - JOUR AU - Campanacci, L. AU - Sambri, A. AU - Medellin, M. R. AU - Cimatti, P. AU - Errani, C. AU - Donati, D. M. PY - 2019 DA - 2019// TI - A new computerized tomography classification to evaluate response to denosumab in giant cell tumors in the extremities JO - Acta Orthop Traumatol Turc VL - 53 UR - https://doi.org/10.1016/j.aott.2019.05.005 DO - 10.1016/j.aott.2019.05.005 ID - Campanacci2019 ER - TY - JOUR AU - Girolami, I. AU - Mancini, I. AU - Simoni, A. AU - Baldi, G. G. AU - Simi, L. AU - Campanacci, D. PY - 2016 DA - 2016// TI - Denosumab treated giant cell tumour of bone: a morphological, immunohistochemical and molecular analysis of a series JO - J Clin Pathol VL - 69 UR - https://doi.org/10.1136/jclinpath-2015-203248 DO - 10.1136/jclinpath-2015-203248 ID - Girolami2016 ER - TY - JOUR AU - Santosh, N. AU - Mayerson, J. L. AU - Iwenofu, O. H. PY - 2016 DA - 2016// TI - Pseudosarcomatous spindle cell proliferation with osteoid matrix mimicking osteosarcoma: a distinct histologic phenotype in giant cell tumor of bone following denosumab therapy JO - Appl Immunohistochem Mol Morphol VL - 24 UR - https://doi.org/10.1097/PAI.0000000000000165 DO - 10.1097/PAI.0000000000000165 ID - Santosh2016 ER - TY - JOUR AU - Okubo, T. AU - Saito, T. AU - Mitomi, H. AU - Takagi, T. AU - Torigoe, T. AU - Suehara, Y. PY - 2013 DA - 2013// TI - p53 mutations may be involved in malignant transformation of giant cell tumor of bone through interaction with GPX1 JO - Virchows Arch VL - 463 UR - https://doi.org/10.1007/s00428-013-1435-z DO - 10.1007/s00428-013-1435-z ID - Okubo2013 ER - TY - JOUR AU - Behjati, S. AU - Tarpey, P. S. AU - Presneau, N. AU - Scheipl, S. AU - Pillay, N. AU - Loo, P. PY - 2013 DA - 2013// TI - Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone JO - Nat Genet VL - 45 UR - https://doi.org/10.1038/ng.2814 DO - 10.1038/ng.2814 ID - Behjati2013 ER - TY - JOUR AU - Cleven, A. H. AU - Hocker, S. AU - Briaire-de Bruijn, I. AU - Szuhai, K. AU - Cleton-Jansen, A. M. AU - Bovee, J. V. PY - 2015 DA - 2015// TI - Mutation analysis of H3F3A and H3F3B as a diagnostic tool for giant cell tumor of bone and chondroblastoma JO - Am J Surg Pathol VL - 39 UR - https://doi.org/10.1097/PAS.0000000000000512 DO - 10.1097/PAS.0000000000000512 ID - Cleven2015 ER - TY - JOUR AU - Nohr, E. AU - Lee, L. H. AU - Cates, J. M. AU - Perizzolo, M. AU - Itani, D. PY - 2017 DA - 2017// TI - Diagnostic value of histone 3 mutations in osteoclast-rich bone tumors JO - Hum Pathol VL - 68 UR - https://doi.org/10.1016/j.humpath.2017.08.030 DO - 10.1016/j.humpath.2017.08.030 ID - Nohr2017 ER - TY - JOUR AU - Chawla, S. AU - Henshaw, R. AU - Seeger, L. AU - Choy, E. AU - Blay, J. Y. AU - Ferrari, S. PY - 2013 DA - 2013// TI - Safety and efficacy of denosumab for adults and skeletally mature adolescents with giant cell tumour of bone: interim analysis of an open-label, parallel-group, phase 2 study JO - Lancet Oncol VL - 14 UR - https://doi.org/10.1016/S1470-2045(13)70277-8 DO - 10.1016/S1470-2045(13)70277-8 ID - Chawla2013 ER - TY - JOUR AU - Thomas, D. AU - Henshaw, R. AU - Skubitz, K. AU - Chawla, S. AU - Staddon, A. AU - Blay, J. Y. PY - 2010 DA - 2010// TI - Denosumab in patients with giant-cell tumour of bone: an open-label, phase 2 study JO - Lancet Oncol. VL - 11 UR - https://doi.org/10.1016/S1470-2045(10)70010-3 DO - 10.1016/S1470-2045(10)70010-3 ID - Thomas2010 ER - TY - JOUR AU - Branstetter, D. G. AU - Nelson, S. D. AU - Manivel, J. C. AU - Blay, J. Y. AU - Chawla, S. AU - Thomas, D. M. PY - 2012 DA - 2012// TI - Denosumab induces tumor reduction and bone formation in patients with giant-cell tumor of bone JO - Clin Cancer Res VL - 18 UR - https://doi.org/10.1158/1078-0432.CCR-12-0578 DO - 10.1158/1078-0432.CCR-12-0578 ID - Branstetter2012 ER - TY - JOUR AU - Sisay, M. AU - Mengistu, G. AU - Edessa, D. PY - 2017 DA - 2017// TI - The RANK/RANKL/OPG system in tumorigenesis and metastasis of cancer stem cell: potential targets for anticancer therapy JO - Onco Targets Ther VL - 10 UR - https://doi.org/10.2147/OTT.S135867 DO - 10.2147/OTT.S135867 ID - Sisay2017 ER - TY - JOUR AU - Raje, N. S. AU - Bhatta, S. AU - Terpos, E. PY - 2019 DA - 2019// TI - Role of the RANK/RANKL pathway in multiple myeloma JO - Clin Cancer Res VL - 25 UR - https://doi.org/10.1158/1078-0432.CCR-18-1537 DO - 10.1158/1078-0432.CCR-18-1537 ID - Raje2019 ER - TY - JOUR AU - Roodman, G. D. PY - 2004 DA - 2004// TI - Mechanisms of bone metastasis JO - N Engl J Med VL - 350 UR - https://doi.org/10.1056/NEJMra030831 DO - 10.1056/NEJMra030831 ID - Roodman2004 ER - TY - JOUR AU - Coleman, R. AU - Finkelstein, D. M. AU - Barrios, C. AU - Martin, M. AU - Iwata, H. AU - Hegg, R. PY - 2020 DA - 2020// TI - Adjuvant denosumab in early breast cancer (D-CARE): an international, multicentre, randomised, controlled, phase 3 trial JO - Lancet Oncol. VL - 21 UR - https://doi.org/10.1016/S1470-2045(19)30687-4 DO - 10.1016/S1470-2045(19)30687-4 ID - Coleman2020 ER -