Skip to main content

Table 2 Summary of exercise prescritption and progression patterns

From: Exercise efficacy and prescription during treatment for pancreatic ductal adenocarcinoma: a systematic review

Author/ date Frequency of exercise prescription Intensity of exercise prescription Time of exercise session Duration of exercise intervention Type of exercise prescribed Exercise intervention setting Progression patterns documented Adverse events / safety
Banzer et al. (2014) 3–5 x/week Moderate (RPE 13–14) 30–45 min 16 weeks Hiking, walking, running, cycling, swimming Home based with option of supervised exercise (Nordic walking) 1x/week Exercise prescription adjusted to their condition, side-effect status and exercise readiness after 4 weeks
No other details provided
Not reported
Cormie et al. (2014) Twice weekly Aerobic: 65–80% HRmax or RPE 11–13 (Borg 6–20)
Resistance: Moderate to high (2–4 sets, 6–12-RM)
Aerobic: 15–20 min 6 months Aerobic (walking or cycling) and resistance (10 exercises, machine based, upper and lower muscle groups) Supervised, exercise clinic 2 one-on-one sessions, followed by group exercise No adverse events reported
Marker et al. (2018) 2–3 x/week Aerobic: < 85% HRmax
Resistance: RPE > 7 (Borg 0–10)
60 mins 17–21 weeks Aerobic (walking, cycling or rowing) and resistance (body weight, machine based, free weights, upper and lower muscle groups) Supervised, unspecified setting No progression described Not reported
McLaughlin et al. (2019) Twice weekly Aerobic: 70% HRmax
Resistance: 3 sets, 12 reps, 60% 1-RM
Aerobic: 15 mins 12 weeks Aerobic (cycling) and resistance (8 exercises, machine based, lower muscle groups only – PICC) Supervised No progression described No adverse events reported
Mouri et al. (2018) Daily Low intensity, 3 sets, 10 reps 30 mins 8 weeks Resistance exercise Unsupervised, home-based Intervention modified by study instructor according to performance and tolerability as identified by self-report diary and interview
Self-modification recommended, based on participants feelings of nausea / fatigue
Adverse events reported in n = 5. Muscle pain (n = 2), arthralgia (n = 1), dyspnoea on exertion (n = 1) plantar aponeurosis (n = 1)
Naito et al. (2018) Daily Low intensity, 3 sets, 10 reps 30 mins 8 weeks Home-based resistance exercise Unsupervised, home-based Intervention modified by study instructor according to performance and tolerability as identified by self-report diary and interview
Self-modification recommended, based on participants feelings of nausea / fatigue
Adverse events reported in n = 5. Muscle pain (n = 2), arthralgia (n = 1), dyspnoea on exertion (n = 1) plantar aponeurosis (n = 1)
Ngo-Huang et al. (2017) Aerobic: 3x/week
Resistance: twice weekly
Aerobic: RPE 12–13
Resistance: 3 sets, 8–12 reps, RPE 12–13
Aerobic: 20 mins
Resistance: 30 mins
Median: 17 weeks (5–35 weeks) Aerobic (walking, cycling, elliptical) and resistance (25 exercises (8 per session), bands, upper and lower muscle groups) Unsupervised, home-based Resistance: increase resistance when 3 × 12 performed without difficulty No adverse events reported
Ngo-Huang et al. (2019) Aerobic: 3x/week
Resistance: twice weekly
Aerobic: RPE 12–13
Resistance: 3 sets, 8–12 reps, RPE 12–13
Aerobic: 20 mins
Resistance: 30 mins
Mean: 16 ± 9 Aerobic (walking, cycling, elliptical) and resistance (25 exercises (8 per session), bands, upper and lower muscle groups) Unsupervised, home-based Resistance: increase resistance when 3 × 12 performed without difficulty No adverse events reported
Niels et al. (2018) Twice weekly Aerobic: 70–80% HRmax, RPE 6–7 (Borg 0–10)
Resistance: 2 sets, 8–12 reps, 70–80% 1-RM
Aerobic: 4–10 min 7 months Aerobic (cycling and cross-trainer) and resistance (6 exercises, machine based, upper and lower muscle groups) Supervised, location not specified No progression described No adverse events reported
Steindorf et al. (2019) Twice weekly Supervised: 1–3 sets, 8–20 reps, 50–80% 1-RM
Unsupervised: 1–3 sets, 8–20 reps, RPE 14–16 (Borg 6–20)
60 mins 6 months Resistance exercise
Supervised: 8 exercises machine based, upper and lower muscle groups
Unsupervised: 8 exercises, bands and dumbbells, upper and lower muscle groups
Supervised: university exercise facility
Unsupervised: home-based
Both Supervised and unsupervised: 4 week adaptation period (5 exercise, 1–2 sets, 20 reps, 50–60% 1-RM. From week 5, 8 exercises, 2–3 sets, 8–12 reps, 60–80% 1-RM.
Supervised: Progressive increase in resistance (5%) after successful completion of 3 sets, 12 reps, 3 consecutive sessions.
No adverse events reported
Wiskemann et al. (2019) Twice weekly Supervised: 1–3 sets, 8–20 reps, 50–80% 1-RM
Unsupervised: 1–3 sets, 8–20 reps, RPE 14–16 (Borg 6–20)
60 mins 6 months Resistance exercise
Supervised: 8 exercises machine based, upper and lower muscle groups
Unsupervised: 8 exercises, bands and dumbbells, upper and lower muscle groups
Supervised: university exercise facility
Unsupervised: home-based
Both Supervised and unsupervised: 4 week adaptation period (5 exercise, 1–2 sets, 20 reps, 50–60% 1-RM. From week 5, 8 exercises, 2–3 sets, 8–12 reps, 60–80% 1-RM.
Supervised: Progressive increase in resistance (5%) after successful completion of 3 sets, 12 reps, 3 consecutive sessions.
No adverse events reported
Yeo et al. (2012) Daily Brisk, unspecified 10–30 min 3 months Aerobic (walking) Unsupervised: home-based, week 1–4: 10 mins
week 5–8: 20 mins
week 9–12: 25–30 min
Not reported