Author/ date | Frequency of exercise prescription | Intensity of exercise prescription | Time of exercise session | Duration of exercise intervention | Type of exercise prescribed | Exercise intervention setting | Progression patterns documented | Adverse events / safety |
---|---|---|---|---|---|---|---|---|
Banzer et al. (2014) | 3–5 x/week | Moderate (RPE 13–14) | 30–45 min | 16 weeks | Hiking, walking, running, cycling, swimming | Home based with option of supervised exercise (Nordic walking) 1x/week | Exercise prescription adjusted to their condition, side-effect status and exercise readiness after 4 weeks No other details provided | Not reported |
Cormie et al. (2014) | Twice weekly | Aerobic: 65–80% HRmax or RPE 11–13 (Borg 6–20) Resistance: Moderate to high (2–4 sets, 6–12-RM) | Aerobic: 15–20 min | 6 months | Aerobic (walking or cycling) and resistance (10 exercises, machine based, upper and lower muscle groups) | Supervised, exercise clinic | 2 one-on-one sessions, followed by group exercise | No adverse events reported |
Marker et al. (2018) | 2–3 x/week | Aerobic: < 85% HRmax Resistance: RPE > 7 (Borg 0–10) | 60 mins | 17–21 weeks | Aerobic (walking, cycling or rowing) and resistance (body weight, machine based, free weights, upper and lower muscle groups) | Supervised, unspecified setting | No progression described | Not reported |
McLaughlin et al. (2019) | Twice weekly | Aerobic: 70% HRmax Resistance: 3 sets, 12 reps, 60% 1-RM | Aerobic: 15 mins | 12 weeks | Aerobic (cycling) and resistance (8 exercises, machine based, lower muscle groups only – PICC) | Supervised | No progression described | No adverse events reported |
Mouri et al. (2018) | Daily | Low intensity, 3 sets, 10 reps | 30 mins | 8 weeks | Resistance exercise | Unsupervised, home-based | Intervention modified by study instructor according to performance and tolerability as identified by self-report diary and interview Self-modification recommended, based on participants feelings of nausea / fatigue | Adverse events reported in n = 5. Muscle pain (n = 2), arthralgia (n = 1), dyspnoea on exertion (n = 1) plantar aponeurosis (n = 1) |
Naito et al. (2018) | Daily | Low intensity, 3 sets, 10 reps | 30 mins | 8 weeks | Home-based resistance exercise | Unsupervised, home-based | Intervention modified by study instructor according to performance and tolerability as identified by self-report diary and interview Self-modification recommended, based on participants feelings of nausea / fatigue | Adverse events reported in n = 5. Muscle pain (n = 2), arthralgia (n = 1), dyspnoea on exertion (n = 1) plantar aponeurosis (n = 1) |
Ngo-Huang et al. (2017) | Aerobic: 3x/week Resistance: twice weekly | Aerobic: RPE 12–13 Resistance: 3 sets, 8–12 reps, RPE 12–13 | Aerobic: 20 mins Resistance: 30 mins | Median: 17 weeks (5–35 weeks) | Aerobic (walking, cycling, elliptical) and resistance (25 exercises (8 per session), bands, upper and lower muscle groups) | Unsupervised, home-based | Resistance: increase resistance when 3 × 12 performed without difficulty | No adverse events reported |
Ngo-Huang et al. (2019) | Aerobic: 3x/week Resistance: twice weekly | Aerobic: RPE 12–13 Resistance: 3 sets, 8–12 reps, RPE 12–13 | Aerobic: 20 mins Resistance: 30 mins | Mean: 16 ± 9 | Aerobic (walking, cycling, elliptical) and resistance (25 exercises (8 per session), bands, upper and lower muscle groups) | Unsupervised, home-based | Resistance: increase resistance when 3 × 12 performed without difficulty | No adverse events reported |
Niels et al. (2018) | Twice weekly | Aerobic: 70–80% HRmax, RPE 6–7 (Borg 0–10) Resistance: 2 sets, 8–12 reps, 70–80% 1-RM | Aerobic: 4–10 min | 7 months | Aerobic (cycling and cross-trainer) and resistance (6 exercises, machine based, upper and lower muscle groups) | Supervised, location not specified | No progression described | No adverse events reported |
Steindorf et al. (2019) | Twice weekly | Supervised: 1–3 sets, 8–20 reps, 50–80% 1-RM Unsupervised: 1–3 sets, 8–20 reps, RPE 14–16 (Borg 6–20) | 60 mins | 6 months | Resistance exercise Supervised: 8 exercises machine based, upper and lower muscle groups Unsupervised: 8 exercises, bands and dumbbells, upper and lower muscle groups | Supervised: university exercise facility Unsupervised: home-based | Both Supervised and unsupervised: 4 week adaptation period (5 exercise, 1–2 sets, 20 reps, 50–60% 1-RM. From week 5, 8 exercises, 2–3 sets, 8–12 reps, 60–80% 1-RM. Supervised: Progressive increase in resistance (5%) after successful completion of 3 sets, 12 reps, 3 consecutive sessions. | No adverse events reported |
Wiskemann et al. (2019) | Twice weekly | Supervised: 1–3 sets, 8–20 reps, 50–80% 1-RM Unsupervised: 1–3 sets, 8–20 reps, RPE 14–16 (Borg 6–20) | 60 mins | 6 months | Resistance exercise Supervised: 8 exercises machine based, upper and lower muscle groups Unsupervised: 8 exercises, bands and dumbbells, upper and lower muscle groups | Supervised: university exercise facility Unsupervised: home-based | Both Supervised and unsupervised: 4 week adaptation period (5 exercise, 1–2 sets, 20 reps, 50–60% 1-RM. From week 5, 8 exercises, 2–3 sets, 8–12 reps, 60–80% 1-RM. Supervised: Progressive increase in resistance (5%) after successful completion of 3 sets, 12 reps, 3 consecutive sessions. | No adverse events reported |
Yeo et al. (2012) | Daily | Brisk, unspecified | 10–30 min | 3 months | Aerobic (walking) | Unsupervised: home-based, | week 1–4: 10 mins week 5–8: 20 mins week 9–12: 25–30 min | Not reported |