Total patients | HPD (n = 26) | SD/PR/CR (n = 129) | P value |
---|---|---|---|
Age (year) | 58.96 ± 10.2 | 65.19 ± 9.1 | 0.002 |
Gender, Female: Male | 3:23 | 35:94 | 0.092 |
Smoking history (pack/y) | 29.3 ± 19.6 | 24.41 ± 21.6 | 0.284 |
  < 20 | 5 | 51 | 0.049 |
  ≥ 20 | 21 | 78 |  |
Histologic subtype | Â | Â | 0.061 |
 Adenocarcinoma | 14 | 93 |  |
 Squamous cell carcinoma | 11 | 34 |  |
 Others | 1 | 2 |  |
Oncogenic driver mutations | Â | Â | Â |
 Yes: No | 8:18 | 16:113 | 0.018 |
 EGFR mutation | 5 | 7 |  |
 ALK, ROS1, and others | 3 | 9 |  |
Number of metastatic sites | Â | Â | 0.005 |
  < 3 | 17 | 113 |  |
  ≥ 3 | 9 | 16 |  |
Prior treatment lines before ICBs | Â | Â | 0.139 |
  < 3 | 21 | 117 |  |
  ≥ 3 | 5 | 12 |  |