Fig. 2

Multiplex immunohistochemistry panels displaying immune compositional changes in tumor microenvironment (n = 24)† . †As explorative setting, some cases with available tissues in HPD, non-HPD PD and PR/CR group. HPD hyperprogressive disease, Non-HPD PD non-HPD progressive disease, PR/CR partial response/complete response, TIL tumor infiltrating lymphocytes, NK natural killer cells, DC dendritic cells