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Fig. 3 | BMC Cancer

Fig. 3

From: Mesothelin blockage by Amatuximab suppresses cell invasiveness, enhances gemcitabine sensitivity and regulates cancer cell stemness in mesothelin-positive pancreatic cancer cells

Fig. 3

Molecular changes in human pancreatic cancer cells exposed to Amatuximab. Western blot analyses in AsPC-1, Capan-2, Panc-1 and MIA Paca-2 cells treated with control IgG or Amatuximab for the indicated proteins related to a cancer stem cells, b survival and chemoresistance, and c epithelial-mesenchymal transition. GADPH was used as an internal control. Ful-length blots are presented in Supplemental Figures 3, 4 and 5. Densitometric analysis of western blots was performed using a ChemiDoc XRS Plus system with Image Lab Software (Bio-Rad, Hercules, CA, USA)

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