Table 3 Multivariate Cox proportional hazard models for the predictors of progression free-survival

Age > 65, yes

0.51 (0.31–0.87)

0.013

0.52 (0.31–0.88)

0.014

Male, yes

1.10 (0.72–1.69)

0.66

1.02 (0.65–1.56)

0.95

Favorable prognosis, yes

1.43 (0.95–2.14)

0.084

1.41 (0.93–2.1)

0.099

Karnofsky performance status ≥90, n (%)

1.18 (0.79–1.76)

0.43

–

–

≥ 2 metastatic sites, n (%)

1.35 (0.90–2.01)

0.15

–

–

Hemoglobin, g/dL

0.98 (0.87–1.10)

0.69

–

–

Leucocytes, 10⁹/L

1.03 (0.92–1.15)

0.59

–

–

Neutrophils, 10⁹/L

1.03 (0.91–1.17)

0.65

–

–

Platelets, 10⁹/L

1.00 (1.00–1.005)

0.044

–

–

Total calcium, mg/dL

1.074 (0.83–1.38)

0.58

–

–

LDH, mg/dL

0.99 (0.99–1.00)

0.28

–

–