Table 1 Toxicology Assessment of R-ketorolac. Hematology results are shown from mice bearing SKOV3ip-RLuc-GFP tumors and treated with placebo or R-ketorolac at 5 mg/kg/d as described in Methods. Control mice were non-tumor bearing and did not receive drug or placebo treatments and are diet, age, and living conditions matched to the other mice on study. Reference ranges are from a strain and age (6–8 weeks) matched Nu/Nu Mouse Biochemistry Technical Sheet from Charles River. Statistical analyses were performed using one-way ANOVA followed by Tukey’s multiple comparisons test. ¹Data points missing due to reported hemolysis error; error may also result when hematocrit levels are high. ²Data averages and standard deviations calculated using Regression on Order Statistics (ROS) model to include points below limit of detection (BLD). *^{, #} Significant difference from placebo and control groups respectively. One, two, three, and four symbols indicates p ≤ 0.05, p ≤ 0.01, p ≤ 0.001, and p ≤ 0.0001, respectively)

From: The R-enantiomer of ketorolac reduces ovarian cancer tumor burden in vivo