Fig. 1

Altered miR-383 and Bcl-2 inversely correlates in GC specimens. RT-qPCR on miR-383 and ELISA for Bcl-2 were performed on paired GC and the adjacent non-tumor gastric tissue (NT) from 50 patients. a-b Bcl-2 levels, shown by individual values (a) and by mean ± SD (b). c-d miR-383 levels, shown by individual values (c) and by mean ± SD (d). For b and d, values were normalized to NT (=1). e ELISA for Bcl-2 in GC with or without LN metastasis. f RT-qPCR for miR-383 in GC with or without LN metastasis. For E and F, values were normalized to GC without LN metastasis (=1). g A Correlation test between relative Bcl-2 and miR-383 levels. Mean level was set up as 50. h A Correlation test between relative Bcl-2 and cleavage Casp3 levels. Mean level was set up as 50. i Kaplan-Meier curve for overall survival. *p < 0.05. **p < 0.01. N = 50