The surgical treatment of non-metastatic melanoma in a Clinical National Melanoma Registry Study Group (CNMR): a retrospective cohort quality improvement study to reduce the morbidity rates

Table 1 Referral values for morbidity rate in the IMI-CNMR study and in the international

Surgical	Indicators	Benchmark referral values
Procedure		Present study	International literature
WE	Wound infection	1.1% (0.4 to 2.7%)	4.6–8.4%^a
	Wound dehiscence	2.0% (0.8 to 5.1%)	3.5–4.6%^a
	Skin graft failure	unreliable	< 2%^a
SLNB	Wound Infection	1.3% (0.7 to 2.5%)	2.9% (1.5 to 4.6%)^b
	Wound dehiscence	0.9% (0.2 to 3.0%)	0.24–1.2%^a
	Seroma	4.2% (1.5 to 11.1%)	5.1% (2.5 to 8.6%)^b
LFND	Wound infection	4.1% (2.1 to 8.0%)	15.8%^a
	Wound dehiscence	2.8% (0.9 to 8.6%)	3%^a
	Wound infection and/or dehiscence	6.5% (2.9 to 14.0%)	21.6% (13.8 to 30.6%)^c
	Seroma	15.1% (4.6 to 39.9%)	17.9% (10.3 to 27%)^c

Data expressed as percentage with 95% confidence interval in parentheses
^aMorton DL, Cochran AJ, Thompson JF, Elashoff R, Essner R, Glass EC, Mozzillo N, Nieweg OE, Roses DF, Hoekstra HJ, Karakousis CP, Reintgen DS, Coventry BJ, Wang HJ; Multicenter Selective Lymphadenectomy Trial Group. Sentinel node biopsy for early-stage melanoma: accuracy and morbidity in MSLT-I, an international multicenter trial. Ann Surg. 2005 Sep;242 (3):302–11; discussion 311–3
^bMoody JA, Ali RF, Carbone AC, Singh S, Hardwicke JT. Complications of sentinel lymph node biopsy for melanoma-A systematic review of the literature. Eur J Surg Oncol. 2017;43:270–277
^cMoody JA, Botham SJ, Dahill KE, Wallace DL, Hardwicke JT. Complications following completion lymphadenectomy versus therapeutic lymphadenectomy for melanoma - A systematic review of the literature. Eur J Surg Oncol. 2017;43:1760–1767