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Fig. 8 | BMC Cancer

Fig. 8

From: The effect of a novel glycolysis-related gene signature on progression, prognosis and immune microenvironment of renal cell carcinoma

Fig. 8

CD44, PLOD1 and PLOD2 can promote the proliferation of renal cancer cells. a The PPI network of eight glycolytic risk genes. b-d The mRNA differential expression of three glycolytic genes in different cell lines. e-g Specific siRNAs inhibit the expression of CD44, PLOD1 and PLOD2 in mRNA levels. h-j Silencing of CD44, PLOD1 and PLOD2 can suppress the proliferation of A498 cells. k-m Silencing of CD44, PLOD1 and PLOD2 can suppress the proliferation of 798-O cells. PPI, protein-protein interaction; NC, negative control; * means p<0.05; * * means p<0.01; * * * means p<0.001

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BMC Cancer

ISSN: 1471-2407

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