Relationship between surgical R0 resectability and findings of peripancreatic vascular invasion on CT imaging after neoadjuvant S-1 and concurrent radiotherapy in patients with borderline resectable pancreatic cancer

Table 5 Relationship between Evans grade and clinicopathological variables

	Evans grade ≤ IIa (n = 21)	Evans grade ≥ IIb (n = 8)	P value
Change in CEA (%)	+ 6% [− 45 − + 140]	−4% [− 54 − + 41]	0.180
Change in CA 19–9 (%)	− 45% [− 85 − + 82]	− 52% [− 94– − 13]	0.262
Change in vascular invasion
shrinkage/stable, progression	4 (19%)/17 (81%)	4 (50%)/4 (50%)	0.164
shrinkage, stable/progression	14 (67%)/7 (33%)	6 (75%)/2 (25%)	1.000
RECIST classification (PR/SD/PD)	2 (10%)/19 (90%)/0	1 (13%)/6 (75%)/1 (13%)	0.242

CEA Carcinoembryonic antigen, CA 19–9 Carbohydrate antigen 19–9, RECIST Response evaluation criteria in solid tumors, PR Partial response, SD Stable disease, PD Progressive disease. Data are presented as n (%) or median [range]

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