Fig. 5
From: Semaphorin 3A mediated brain tumor stem cell proliferation and invasion in EGFRviii mutant gliomas
Nrp1-KD and PlxnA1-KD tumors in athymic nude mice flanks. a Shows decreased mean tumor diameter in both receptor knockdowns. NT tumor diameter was statistically significantly greater than Nrp1-KD at all time points after week 3, while comparison with PlxnA1-KD approached significance following week 5. b Scatter plot of flank tumor diameters at week 7. c Mean tumor weight. d Sample images of tumors in mice. Black arrows point to tumors. n = 5 per arm (one NT mouse died of non-tumor related causes at the start of the experiment; **p < 0.005)