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Fig. 6 | BMC Cancer

Fig. 6

From: MNAT1 promotes proliferation and the chemo-resistance of osteosarcoma cell to cisplatin through regulating PI3K/Akt/mTOR pathway

Fig. 6

MNAT1 regulated PI3K/Akt/mTOR signaling pathway in OS. a KEGG analysis the different regulated signaling pathways in OS tumor compared with adjacent non-tumor tissues. b GSEA analysis the enrichment of signature genes in MNAT1 high or low group. c PI3K/Akt/mTOR pathway related proteins were analyzed by western blot. d IHC staining of PI3K, AKT and mTOR in xenograft tumor tissues from NC or sh-MNAT1 group. e The expression of MNAT1 was evaluated by western blot assay. * p < 0.05; ** p < 0.01

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