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Fig. 3 | BMC Cancer

Fig. 3

From: MNAT1 promotes proliferation and the chemo-resistance of osteosarcoma cell to cisplatin through regulating PI3K/Akt/mTOR pathway

Fig. 3

MNAT1 knockdown suppressed OS cell proliferation and migration. a The transfection efficiency of the MNAT1 siRNA was evaluated by qRT-PCR and western blot. b and c The changes in the proliferation of OS cells transfected with si-MNAT1 or NC were determined by the CCK-8 assay. d EdU staining assays (Scale bars, 50 μm) and e colony formation assays (Scale bars, 8 mm) were performed to determine the growth of U2OS and 143B cells. f Cell migration was assessed by wound-healing assay (Scale bars, 500 μm). g Cell invasion was assessed by transwell assay (Scale bars, 50 μm). *p < 0.05, **p < 0.01

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BMC Cancer

ISSN: 1471-2407

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