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Fig. 3 | BMC Cancer

Fig. 3

From: Distinct mutation profiles between primary bladder cancer and circulating tumor cells warrant the use of circulating tumors cells as cellular resource for mutation follow-up

Fig. 3

Three mutation categories and mutation analysis. (a) Consequences of somatic mutations on encoded peptide sequences are categorized and relative proportions are shown across three regional mutation categories (common, primary-specific, and CTC-specific). (b) Similarly shown for six mutation spectra. (c) Mutation signature levels estimated across mutation categories are shown in a heatmap with a dendrogram. Two arrows indicate signatures of 2 and 13. (d). Mutation allele frequencies of mutations are shown as clonality measures

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BMC Cancer

ISSN: 1471-2407

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