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Table 1 Study cohort (n = 17,747)

From: Epithelial splicing regulatory protein 1 and 2 (ESRP1 and ESRP2) upregulation predicts poor prognosis in prostate cancer

 

No. of patients (%)

Study cohort on TMA

Biochemical relapse among categories

(n = 17,747)

 

Follow-up (mo)

 n

14,464 (81.5%)

3612 (25%)

 Mean

56.3

 Median

48

Age (y)

  ≤ 50

433 (2.4%)

66 (15.2%)

 51–59

4341 (24.5%)

839 (19.3%)

 60–69

9977 (56.4%)

2073 (20.8%)

  ≥ 70

2936 (16.6%)

634 (21.6%)

Pretreatment PSA (ng/ml)

  < 4

2225 (12.6%)

313 (14.1%)

 4–10

10,520 (59.6%)

1696 (16.1%)

 10–20

3662 (20.8%)

1043 (28.5%)

  > 20

1231 (7%)

545 (44.3%)

pT stage (AJCC 2002)

 pT2

11,518 (65.2%)

1212 (10.5%)

 pT3a

3842 (21.7%)

1121 (29.2%)

 pT3b

2233 (12.6%)

1213 (54.3%)

 pT4

85 (0.5%)

63 (74.1%)

Gleason grade

  ≤ 3 + 3

3570 (20.3%)

264 (7.4%)

 3 + 4

9336 (53%)

1436 (15.4%)

 3 + 4 Tert.5

798 (4.5%)

165 (20.7%)

 4 + 3

1733 (9.8%)

683 (39.4%)

 4 + 3 Tert.5

1187 (6.7%)

487 (41%)

  ≥ 4 + 4

999 (5.7%)

531 (53.2%)

pN stage

 pN0

10,636 (89.4%)

2243 (21.1%)

 pN+

1255 (10.6%)

700 (55.8%)

Surgical margin

 Negative

14,297 (80.8%)

2307 (16.1%)

 Positive

3388 (19.2%)

1304 (38.5%)

  1. NOTE: Percent in the column “Study cohort on TMA” refers to the fraction of samples across each category. Percent in colum “Biochemical relaps among categories” refers to the fraction of samples with biochemical relaps within each parameter in the different categories. Numbers do not always add up to 17,747 in the different categories because of cases with missing data. Abbreviation: AJCC American Joint Committee on Cancer