Table 1 Demographics of patients
Patients, n | 1104 |
|---|---|
Age (median [IQR]) | 69.00 [60.00, 76.00] |
Sex | |
female | 410 (37.1) |
male | 694 (62.9) |
Stage at diagnosis | |
UICC I | 34 (3.1) |
UICC II | 91 (8.2) |
UICC III | 263 (23.8) |
UICC IV | 716 (64.9) |
Time to metastasis | |
DFS < 6 mts | 771 (69.8) |
DFS > 6 mts | 333 (30.2) |
Treatment modality | |
best supportive care | 274 (24.8) |
resection of metastases only | 84 (7.6) |
systemic treatment and resection of metastases | 144 (13.0) |
systemic treatment only | 602 (54.5) |
Treatment lines | |
first line treatment | 746 (67.6) |
second line treatment | 465 (42.1) |
third line treatment | 261 (23.6) |
RAS-status | |
RAS-mutated | 453 (41.0) |
RAS-wildtype | 426 (38.6) |
unknown | 225 (20.4) |
BRAF-status (%) | |
BRAF-mutated | 42 (3.8) |
BRAF-wildtype | 364 (33.0) |
unknown | 698 (63.2) |
MMR-status | |
microsatellite instable | 26 (2.4) |
microsatellite stable | 180 (16.3) |
unknown | 898 (81.3) |
Location of primary | |
colon | 699 (64.2) |
rectum | 389 (35.8) |
LCC | 762 (70.0) |
RCC | 326 (30.0) |
Organs with metastases | |
1 organ | 784 (71.0) |
2 or more organs | 320 (29.0) |
Lung only metastases | |
lung only | 111 (10.1) |
other than lung only | 993 (89.9) |