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Table 4 Association of age, BMI and primary tumor size with achieving pCR

From: Addition of carboplatin-gemcitabine as second-line neoadjuvant chemotherapy in non-responsive locally advanced breast cancer patients to standard neoadjuvant chemotherapy and evaluation of factors affecting response: a randomized controlled trial

Factor group response to NAC P value
pCR non-pCR
Age (mean ± SD) Control n = 27 41.37 ± 5.47 46.52 ± 9.01 0.147
Intervention n = 25 46.12 ± 5.56 38.65 ± 8.86 0.04
Total n = 52 43.75 ± 5.87 42.8 ± 9.67 0.655
BMI
(mean ± SD)
Control n = 27 28.05 ± 3.73 27.1 ± 4.69 0.618
Intervention n = 25 25.85 ± 3.09 27.17 ± 4.39 0.344
Total n = 52 28.45 ± 3.34 27.14 ± 4.49 0.301
Primary tumor size (mean ± SD) Control n = 27 23.8 ± 12.65 34.45 ± 21.31 0.205
Intervention n = 25 28.12 ± 19.15 47.29 ± 36.42 0.178
Total n = 52 26 ± 15.83 40.5 ± 29.7 0.065
  1. BMI body mass index, pCR pathologic complete response