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Table 4 Association of age, BMI and primary tumor size with achieving pCR

From: Addition of carboplatin-gemcitabine as second-line neoadjuvant chemotherapy in non-responsive locally advanced breast cancer patients to standard neoadjuvant chemotherapy and evaluation of factors affecting response: a randomized controlled trial

Factor

group

response to NAC

P value

pCR

non-pCR

Age (mean ± SD)

Control n = 27

41.37 ± 5.47

46.52 ± 9.01

0.147

Intervention n = 25

46.12 ± 5.56

38.65 ± 8.86

0.04

Total n = 52

43.75 ± 5.87

42.8 ± 9.67

0.655

BMI

(mean ± SD)

Control n = 27

28.05 ± 3.73

27.1 ± 4.69

0.618

Intervention n = 25

25.85 ± 3.09

27.17 ± 4.39

0.344

Total n = 52

28.45 ± 3.34

27.14 ± 4.49

0.301

Primary tumor size (mean ± SD)

Control n = 27

23.8 ± 12.65

34.45 ± 21.31

0.205

Intervention n = 25

28.12 ± 19.15

47.29 ± 36.42

0.178

Total n = 52

26 ± 15.83

40.5 ± 29.7

0.065

  1. BMI body mass index, pCR pathologic complete response