Table 3 Summary of SNHG15 with their aberrant expression,biological functions, and related signaling pathways
From: Long non-coding RNA SNHG15 in various cancers: a meta and bioinformatic analysis
Study | Cancer | Expression | biological functions | related signaling pathways |
|---|---|---|---|---|
Chen 2016 [21] | gastric cancer | upregulation | promote cell proliferation and invasion, inhibit apoptosis | MMP2/MMP9 |
Cui 2018 [23] | lung cancer | upregulation | promote cell proliferation,invasion | microRNA-211-3p |
Dong 2018 [24] | non-small cell lung cancer | upregulation | promote cell proliferation, invasion and metastasis, inhibit apoptosis. | EMT/MMP2/MMP9 |
Du 2018 [26] | renal cell carcinoma | upregulation | promote cell proliferation, invasion and migration | EMT/NF-κB |
Jin 2018 [25] | non-small cell lung cancer | upregulation | promote cell proliferation, induce apoptosis and cycle arrest at G0/G1 phase | miR-486/CDK14 |
Kong 2018 [28] | breast cancer | upregulation | promote cell proliferation, migration,invasion and induce apoptosis | miR-211-3p/EMT |
Wu 2018 [29] | papillary thyroid cancer | upregulation | promote cell growth and migration | miR-200a-3p/YAP1-Hippo |
Qu 2019 [31] | epithelial ovarian cancer | upregulation | promote cell migration, invasion, proliferation and induce chemoresistance | – |