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Table 4 Association of social mobility with the risk of BC in E3N using imputed data (N = 83,436)

From: The impact of lifecourse socio-economic position and individual social mobility on breast cancer risk

   

E3N

Model 1

Model 1 + HB-A

Model 1 + RF

Fully adjusted model

Covariates

Reference

Modality

HR [95%CI]

HR [95%CI]

HR [95%CI]

HR [95%CI]

Social mobility

Stable disadvantaged SEP

Downward mobility

1.06 [0.95; 1.19]

1.04 [0.93; 1.17]

1.00 [0.90; 1.12]

1.00 [0.89; 1.12]

  

Stable medium SEP

1.02 [0.92; 1.12]

1.01 [0.91; 1.11]

0.96 [0.87; 1.06]

0.96 [0.87; 1.06]

  

Upward mobility

1.04 [0.94; 1.14]

1.03 [0.93; 1.13]

1.00 [0.91; 1.10]

0.99 [0.90; 1.09]

  

Stable advantaged SEP

1.24 [1.07; 1.43]

1.20 [1.04; 1.39]

1.15 [0.99; 1.33]

1.13 [0.98; 1.31]

  1. Model 1 is adjusted for age and social mobility
  2. Model 1 + HB-A is adjusted for age, social mobility, alcohol consumption, smoking status, physical activity, Western diet pattern, height, weight
  3. Model 1 + RF is adjusted for age, social mobility, family history of ovarian cancer or BC, MHT use, breastfeeding, cancer screening, reproductive lifespan, age at first childbirth and menopausal status
  4. Fully adjusted model is adjusted for age, social mobility and all covariates