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Table 1 Characteristics of women with available data from E3N according to BC status

From: The impact of lifecourse socio-economic position and individual social mobility on breast cancer risk

Variables

BC

 

p

 

No

Yes

 

Father s occupation (3 cl)

n = 55,766

n = 5957

0.025

 Advantaged, n(%)

9294 (16.67)

1075 (18.05)

 

 Medium, n(%)

23,619 (42.35)

2492 (41.83)

 

 Disadvantaged, n(%)

22,853 (40.98)

2390 (40.12)

 

Education (3 cl)

n = 72,773

n = 7577

< 0.001

 High, n(%)

26,096 (35.86)

2913 (38.45)

 

 Middle, n(%)

36,422 (50.05)

3745 (49.43)

 

 Low, n(%)

10,255 (14.09)

919 (12.13)

 

Occupation (3 cl)

n = 62,726

n = 6700

0.017

 Advantaged, n(%)

10,962 (17.48)

1250 (18.66)

 

 Medium, n(%)

40,679 (64.85)

4332 (64.66)

 

 Disadvantaged, n(%)

11,085 (17.67)

1118 (16.69)

 

Age

n = 75,559

n = 7877

< 0.001

  < 47.9y, n(%)

39,491 (52.27)

3837 (48.71)

 

  ≥ 47.9y, n(%)

36,068 (47.73)

4040 (51.29)

 

Alcohol consumption

n = 71,357

n = 7455

< 0.001

 Abstainer, n(%)

7040 (9.87)

678 (9.09)

 

 Moderate, n(%)

38,720 (54.26)

4167 (55.9)

 

 High, n(%)

10,975 (15.38)

1356 (18.19)

 

 Not responding to Q3, n(%)

14,622 (20.49)

1254 (16.82)

 

Smoking status

n = 75,333

n = 7850

0.693

 Never, n(%)

50,531 (67.08)

5269 (67.12)

 

 Former, n(%)

15,204 (20.18)

1560 (19.87)

 

 Ever, n(%)

9598 (12.74)

1021 (13.01)

 

Western diet pattern

n = 71,358

n = 7455

< 0.001

 [−2.93,-0.511], n(%)

18,876 (26.45)

1921 (25.77)

 

 (−0.511,0.307], n(%)

18,868 (26.44)

2089 (28.02)

 

 (0.307,7.78], n(%)

18,991 (26.61)

2191 (29.39)

 

 Not responding to Q3, n(%)

14,623 (20.49)

1254 (16.82)

 

Physical activity (MET)

n = 74,540

n = 7768

< 0.001

 (7.57,35.9], n(%)

25,040 (33.59)

2395 (30.83)

 

 (4.66,7.57], n(%)

24,635 (33.05)

2630 (33.86)

 

 [0,4.66], n(%)

24,865 (33.36)

2743 (35.31)

 

Height

n = 74,316

n = 7759

< 0.001

 [135,160], n(%)

33,983 (45.73)

3355 (43.24)

 

 (160,164], n(%)

16,551 (22.27)

1732 (22.32)

 

 (164,190], n(%)

23,782 (32)

2672 (34.44)

 

Weight

n = 73,847

n = 7715

0.076

 [29,55], n(%)

25,135 (34.04)

2530 (32.79)

 

 (55,62], n(%)

24,737 (33.5)

2611 (33.84)

 

 (62,163], n(%)

23,975 (32.47)

2574 (33.36)

 

Previous ovary cancer (1grade)

n = 75,559

n = 7877

0.002

 No, n(%)

74,709 (98.88)

7757 (98.48)

 

 Yes, n(%)

850 (1.12)

120 (1.52)

 

Previous breast cancer (1grade)

n = 73,693

n = 7673

< 0.001

 No, n(%)

31,622 (42.91)

3039 (39.61)

 

 Yes, n(%)

5240 (7.11)

886 (11.55)

 

 Not available, n(%)

36,831 (49.98)

3748 (48.85)

 

MHT use

n = 67,245

n = 7111

< 0.001

 No, n(%)

58,868 (87.54)

6021 (84.67)

 

 Yes, n(%)

6029 (8.97)

806 (11.33)

 

 Undefined, n(%)

2348 (3.49)

284 (3.99)

 

Number of full term pregnancy

n = 75,551

n = 7877

< 0.001

 3+, n(%)

22,212 (29.4)

2000 (25.39)

 

 1–2, n(%)

44,491 (58.89)

4827 (61.28)

 

 0, n(%)

8848 (11.71)

1050 (13.33)

 

Age at the first childbirth

n = 73,018

n = 7660

< 0.001

  [14, 23], n(%)

26,390 (36.14)

2445 (31.92)

 

 (23,26], n(%)

19,487 (26.69)

1959 (25.57)

 

 (26,59], n(%)

18,293 (25.05)

2206 (28.8)

 

 No preg, n(%)

8848 (12.12)

1050 (13.71)

 

Combined age and number of pregnancy

n = 73,016

n = 7660

< 0.001

 Early first birth and high number of children, n(%)

11,119 (15.23)

938 (12.25)

 

 High number of children, n(%)

10,150 (13.9)

997 (13.02)

 

 Late first birth and few number of children, n(%)

14,575 (19.96)

1794 (23.42)

 

 Low number of children, n(%)

28,324 (38.79)

2881 (37.61)

 

 No pregnancy, n(%)

8848 (12.12)

1050 (13.71)

 

Breastfeeding

n = 67,708

n = 7189

0.019

 Yes, n(%)

40,113 (59.24)

4156 (57.81)

 

 No, n(%)

27,595 (40.76)

3033 (42.19)

 

Reproductive lifespan

n = 69,697

n = 7508

< 0.001

 [27; 41[, n(%)

56,083 (80.47)

5964 (79.44)

 

  < 27, n(%)

1161 (1.67)

80 (1.07)

 

  ≥ 41, n(%)

12,453 (17.87)

1464 (19.5)

 

Breast cancer screening

n = 75,559

n = 7877

< 0.001

 Yes, n(%)

52,720 (69.77)

6012 (76.32)

 

 No, n(%)

22,839 (30.23)

1865 (23.68)

 

Postmenopausal status

n = 71,368

n = 7675

0.016

 Pre-menopausal, n(%)

41,683 (58.41)

4593 (59.84)

 

 Post-menopausal, n(%)

29,685 (41.59)

3082 (40.16)

 
  1. P-values are estimated with log rank tests