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Table 2 Expression of Kv2.1 and Kv1.5 proteins and clinico-pathological features of patients with GC

From: Selective expression of KCNA5 and KCNB1 genes in gastric and colorectal carcinoma

Parameters Kv2.1 protein, N = 40 (%) P a Kv1.5 protein, N = 40 (%) P a
Negative Mildly Positive Moderately Positive Strongly Positive Negative Mildly positive Moderately positive Strongly positive
Gender
 Male 8 (20) 3 (7.5) 10 (25) 5 (12.5) 0.36 6 (15) 5 (12.5) 11 (27.5) 4 (10) 0.64
 Female 7 (17.5) 3 (7.5) 3 (7.5) 1 (2.5) 6 (15) 2 (5) 4 (10) 2 (5)
Age (years)
 < 50 5 (12.5) 2 (5) 6 (15) 2 (5) 0.89 6 (15) 2 (5) 5 (12.5) 2 (5) 0.75
 ≥ 50 10 (25) 4 (10) 7 (17.5) 4 (10) 6 (15) 5 (15.5) 10 (25) 4 (10)
Lauren classification
 Diffuse 8 (20) 3 (7.5) 7 (17.5) 2 (5) 0.78 7 (17.5) 4 (10) 7 (17.5) 2 (5) 0.94
 Intestinal 5 (12.5) 3 (7.5) 3 (7.5) 3 (7.5) 4 (10) 2 (5) 5 (12.5) 3 (7.5)
 Mixed 2 (5) 0 (0) 3 (7.5) 1 (2.5) 1 (2.5) 1 (2.5) 3 (7.5) 1 (2.5)
Tumor localization
 Antro-Pyloric 4 (10.5) 0 (0) 4 (10.5) 4 (10.5) 0.09 1 (2.6) 4 (10.5) 5 (13.2) 2 (5.3) 0.36
 Cardia 1 (2.6) 2 (5.3) 1 (2.6) 0 (0) 1 (2.6) 1 (2.6) 2 (5.3) 0 (0)  
 Antro-fundic 9 (23.7) 4 (10.5) 8 (21.1) 1 (2.6) 9 (23.7) 2 (5.3) 7 (18.4) 4 (10.5)  
TNM classification
 Early/localized stage (I, II) 6 (19.4) 4 (12.9) 10 (32.3) 4 (12.9) 0.026 4 (12.9) 5 (16.1) 11 (35.5) 4 (12.9) 0.056
 Advanced/metastatic stage (III, VI) 6 (19.4) 0 (0) 0 (0) 1 (2.6) 4 (12.9) 1 (3.2) 0 (0) 2 (6.5)
Differentiation
 Poorly 10 (25) 3 (7.5) 8 (20) 2 (5) 0.41 8 (20) 5 (12.5) 8 (20) 2 (5) 0.48
 Moderately 3 (7.5) 2 (5) 4 (10) 1 (2.5) 2 (5) 0 (0) 5 (12.5) 3 (7.5)
 Well 2 (5) 1 (2.5) 1 (2.5) 3 (7.5) 2 (5) 2 (0) 2 (5) 1 (2.5)
Tumour infiltration
 pT1-T2 4 (12.9) 3 (9.7) 6 (19.4) 3 (9.7) 0.41 2 (6.5) 3 (9.7) 8 (25.8) 3 (9.7) 0.24
 pT3-T4 8 (25.8) 1 (3.2) 4 (12.9) 2 (6.5) 6 (19.4) 3 (9.7) 3 (9.7) 3 (9.7)
Metastasis
 Absent 11 (27.5) 6 (15) 13 (32.5) 6 (15) 0.06 9 (22.5) 7 (17.5) 15 (37.5) 5 (12.5) 0.087
 Present 4 (10) 0 (0) 0 (0) 0 (0) 3 (7.5) 0 (0) 0 (0) 1 (2.5)
  1. TNM Tumor, Nodes, Metastases according to the American Joint Committee on Cancer (AJCC), a Pearson chi square (categorical variables)