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Table 5 Acute toxicity

From: Impact of superselective intra-arterial and systemic chemoradiotherapy for gingival carcinoma; analysis of treatment outcomes and prognostic factors

Acute Toxicities

IACRT group

SCRT group

P value

≤ Grade 1

Grade 2

Grade 3

≥ Grade 4

≤ Grade 1

Grade 2

Grade 3

≥ Grade 4

≥ Grade 3

Hematologic toxicity

 Anemia

21 (31.8%)

35 (53.1%)

10 (15.1%)

0

6 (33.3%)

11 (61.1%)

1 (5.6%)

0

0.24

 leukopenia

23 (34.8%)

19 (28.8%)

19 (28.8%)

5 (7.6%)

14 (77.7%)

3 (16.7%)

1 (5.6%)

0

0.012

 Neutropenia

37 (56.1%)

15 (22.7%)

13 (19.7%)

1 (1.5%)

17 (94.4%)

0

1 (5.6%)

0

0.13

 lymphopenia

6 (9.1%)

12 (18.2%)

26 (39.4%)

22 (33.3%)

7 (38.8%)

1 (5.6%)

10 (55.6%)

0

0.21

 thrombopenia

61 (92.5%)

2 (3.0%)

3 (4.5%)

0

18 (100%)

0

0

0

0.37

General conditions

 Radiation dermatitis

25 (37.9%)

27 (40.9%)

12 (18.2%)

2 (3.0%)

8 (%)

10 (%)

0

0

0.034

 Oral mucositis

2 (3.0%)

20 (30.3%)

43 (65.2%)

1 (1.5%)

3 (16.7%)

7 (38.8%)

7 (38.8%)

1 (5.6%)

0.088

 Xerostomia

43 (65.2%)

20 (30.3%)

2 (3.0%)

0

10 (55.6%)

8 (44.4%)

0

0

0.46

 Dysphagia

0

17 (25.8%)

49 (74.2%)

0

0

11 (61.1%)

7 (38.8%)

0

0.008

  1. IACRT Intra-arterial chemoradiation, SCRT systemic chemoradiation therapy