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Table 3 Peri−/postoperative morbidities according to CTCAE

From: Pressurized intraperitoneal aerosol chemotherapy (PIPAC) for rare gynecologic indications: peritoneal metastases from breast and endometrial cancer

Adverse Events CTCAE Grade
1 2 3 4 5
Abdominal pain 50 20
Anemia 1 3
Appetite loss 1
Bowel obstruction 1 1
Cachexia 1
Cutaneous abscess 1
Diarrhea 2
Dyspnea 7 2 1
Fatigue 1
Nausea 31 3
Pleural effusion 2 1
Pneumonia 2
Pulmonary embolism 1
Exacerbation of radiation proctitis 1
Small bowel perforation a 1
Trocar wound complications 4 1
Tachycardia 1
Thrombosis (lower extremity) 2
Urinary tract infection 1 2
Other 5 2
Total (N = 151) 103 36 10 2 0
  1. Values are counts. CTCAE Common Terminology Criteria for Adverse Events (Version 4.03). aOne case of small bowel perforation during laparoscopic PIPAC access occurred. The lesion was recognized and repaired via mini-laparotomy and PIPAC was resumed