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Table 1 Association of voided urine cytology with clinicopathological characteristics in UTUC patients

From: Preoperative positive voided urine cytology predicts poor clinical outcomes in patients with upper tract urothelial carcinoma undergoing nephroureterectomy

 

Urine Cytology

Negative (%)

Positive (%)

P value

Gender

 Male

126 (41.1)

66 (34.7)

0.27

 Female

88 (58.9)

35 (65.3)

Age (years)

 <65

88 (41.1)

33 (32.4)

0.15

  ≥ 65

126 (58.9)

68 (67.3)

Smoking history

 No

141 (65.9)

64 (63.4)

0.7

 Yes

73 (34.1)

37 (36.6)

Alcohol history

 No

164 (76.6)

70 (69.3)

0.17

 Yes

50 (23.4)

31 (30.7)

Hematuria

 No

45 (21.0)

8 (7.9)

0.004

 Yes

169 (79.0)

93 (92.1)

Hypertension

 No

139 (65.0)

55 (54.5)

0.074

 Yes

75 (35.0)

46 (45.5)

Diabetes mellitus

 No

182 (85.0)

84 (83.2)

0.7

 Yes

32 (15)

17 (16.8)

Body mass index

 <30

194 (90.7)

93 (92.1)

0.7

  ≥ 30

20 (9.3)

8 (7.9)

Hydronephrosis

 No

76 (35.5)

40 (39.6)

0.5

 Yes

138 (64.5)

61 (60.4)

Multifocality

 Unifocal

200 (93.5)

86 (85.1)

0.017

 Multifocal

14 (6.5)

15 (14.9)

Size

  ≤ 2 CM

59 (27.6)

25 (24.8)

0.6

 >2 CM

155 (72.4)

76 (75.2)

Bladder instillation

 No

49 (22.9)

26 (25.7)

0.6

 Yes

165 (77.1)

75 (74.3)

Pathologic tumor stage

  ≤ T2

114 (53.3)

45 (44.6)

0.15

  ≥ T3

100 (46.7)

56 (55.4)

Tumor grade

 Low grade

61 (29.2)

15 (15.5)

0.010

 High grade

148 (70.8)

82 (84.5)

Location

 Renal pelvis

101 (48.1)

54 (57.4)

0.13

 Ureter

109 (51.9)

40 (42.6)

Preoperative URS

 No

160 (74.8)

84 (83.2)

0.10

 Yes

54 (25.2)

17 (16.8)

LVI

 No

62 (59.0)

35 (64.8)

0.5

 Yes

43 (41.0)

19 (35.2)

  1. LVI Lymphovascular invasion; CM Centimeter; URS Ureteroscopy