Skip to main content

Table 2 Preceding Healthcare Encounters, Tests, Blood Bank Utilization and Systemic Antibiotic Administration (N = 11,183 cultures)

From: Development and utility assessment of a machine learning bloodstream infection classifier in pediatric patients receiving cancer treatments

  Negative Positive P*
N 10,559 624  
Location where Culture Obtained    < 0.001
 Clinic 1346 (12.7) 62 (9.9)  
 Emergency Department 4877 (46.2) 219 (35.1)  
 Intensive Care Unit 329 (3.1) 9 (1.4)  
 Hospital Ward 4007 (37.9) 334 (53.5)  
Healthcare Encounters within 28 Days
 Mean Number Emergency Department Visits (SD) 0.35 (0.62) 0.28 (0.54) 0.006
 Mean Number Admissions (SD) 0.53 (0.71) 0.57 (0.67) 0.178
 Mean All Encounters (SD) 3.95 (3.32) 3.86 (3.06) 0.474
Tests Performed within 28 Days
 Mean Pathology Specimens (SD) 0.24 (0.77) 0.39 (1.04) < 0.001
 Mean Radiology Tests (SD) 1.12 (2.07) 1.37 (2.14) 0.003
Blood Bank Utilization within 7 Days
 Mean Platelet Transfusions (SD) 0.40 (1.20) 1.15 (1.78) < 0.001
 Mean Red Cell Transfusions (SD) 0.28 (0.80) 0.53 (0.91) < 0.001
Previous Positive Blood Cultures 7–365 Days
 Mean Positive Cultures (SD) 0.65 (1.95) 1.18 (2.22) < 0.001
Systemic Antibiotics within 7 Days
 FN Antibiotics One Day Prior (%) 273 (2.6) 11 (1.8) 0.255
 FN Antibiotics Two Days Prior (%) 250 (2.4) 14 (2.2) 0.950
 Mean Days FN Antibiotics (SD) 0.24 (0.86) 0.35 (0.94) 0.001
 Antifungal One Day Prior (%) 1008 (9.5) 210 (33.7) < 0.001
 Antifungal Two Days Prior (%) 936 (8.9) 208 (33.3) < 0.001
 Mean Days Antifungal (SD) 0.56 (1.56) 1.94 (2.56) < 0.001
 Levofloxacin One Day Prior (%) 36 (0.3) 8 (1.3) 0.001
 Levofloxacin Two Days Prior (%) 45 (0.4) 5 (0.8) 0.291
 Mean Days Levofloxacin (SD) 0.02 (0.25) 0.08 (0.50) < 0.001
 Caspofungin One Day Prior (%) 380 (3.6) 55 (8.8) < 0.001
 Caspofungin Two Days Prior (%) 349 (3.3) 56 (9.0) < 0.001
 Mean Days Caspofungin (SD) 0.22 (1.01) 0.56 (1.58) < 0.001
  1. Abbreviations: SD Standard deviation, FN Fever and neutropenia
  2. *P values calculated using Student’s t-test for continuous variables and chi square test for categorical variables
\