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Table 2 Cox proportional hazards model of distant disease-free interval: outcome = rMBCa (n = 6603)

From: Breast cancer distant recurrence lead time interval by detection method in an institutional cohort

By order of entry into the model: HzR (95% CI) p value Wald chi-square Model Chi-square change df
TNM Stage I reference <.001 200.86 353.10 2
TNM Stage II 3.30 (2.47, 4.42)   64.96   
TNM Stage III 9.19 (6.70, 12.60)   190.03   
HR/HER2 status: initial diagnosis
 HR+/HER2- reference <.001 48.50 55.00 2
 HR+ or HR−/HER2+ .86 (.66, 1.13)   1.13   
 HR−/HER2- 2.22 (1.73, 2.84)   40.31   
Histological grade primary tumor
 Low/Intermediate reference <.001 7.89 29.04 1
 High 1.49 (1.13, 1.98)     
Detection method
 MamD reference <.001 25.84 8.51 1
 PtD 1.80 (1.43, 2.25)     
  1. aadjusted for age, race and diagnosis year (not significant in the model)