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Table 2 Cox proportional hazards model of distant disease-free interval: outcome = rMBCa (n = 6603)

From: Breast cancer distant recurrence lead time interval by detection method in an institutional cohort

By order of entry into the model:

HzR (95% CI)

p value

Wald chi-square

Model Chi-square change

df

TNM Stage I

reference

<.001

200.86

353.10

2

TNM Stage II

3.30 (2.47, 4.42)

 

64.96

  

TNM Stage III

9.19 (6.70, 12.60)

 

190.03

  

HR/HER2 status: initial diagnosis

 HR+/HER2-

reference

<.001

48.50

55.00

2

 HR+ or HR−/HER2+

.86 (.66, 1.13)

 

1.13

  

 HR−/HER2-

2.22 (1.73, 2.84)

 

40.31

  

Histological grade primary tumor

 Low/Intermediate

reference

<.001

7.89

29.04

1

 High

1.49 (1.13, 1.98)

    

Detection method

 MamD

reference

<.001

25.84

8.51

1

 PtD

1.80 (1.43, 2.25)

    
  1. aadjusted for age, race and diagnosis year (not significant in the model)