From: Breast cancer distant recurrence lead time interval by detection method in an institutional cohort
 | PtD | MamD | p value |
---|---|---|---|
(n = 2566) | (n = 4037) | ||
Stage | N (column %) | N (column %) | Â |
 I | 792 (31%) | 2772 (69%) | <.001 |
 II | 1314 (51%) | 1108 (27%) |  |
 III | 460 (18%) | 157 (4%) |  |
Age | |||
 40–49 | 950 (55%) | 765 (45%) | <.001 |
 50–64 | 1216 (36%) | 2189 (64%) |  |
 65–74 | 400 (27%) | 1083 (73%) |  |
 Mean age (range, F statistic) | 54 (40–74) | 58 (40–74) | <.001 |
Race | |||
 White | 1986 (37%) | 3388 (63%) | <.001 |
 Non-White | 580 (47%) | 649 (53%) |  |
Hormone receptor status | |||
 HR+ | 2081 (36%) | 3641 (64%) | <.001 |
HER2 status | |||
 Her2+ (HR- or HR+) | 458 (46%) | 534 (54%) | <.001 |
HR/HER2 status at initial diagnosis | |||
 HR+/HER2- | 1718 (36%) | 3110 (64%) | <.001 |
 HR+/HER2+ | 332 (45%) | 399 (55%) |  |
 HR−/HER2- | 340 (61%) | 216 (39%) |  |
 HR−/HER2+ | 126 (49%) | 134 (51%) |  |
Histologic type initial primary breast tumor | |||
 Ductal | 2122 (39%) | 3312 (61%) | .287 |
 Lobular | 258 (39%) | 411 (61%) |  |
 Lobular/Ductal mixed | 120 (40%) | 177 (60%) |  |
 Other cancer | 64 (33%) | 133 (67%) |  |
Nuclear grade initial primary breast tumor | |||
 Low/Intermediate | 1189 (31%) | 2675 (69%) | <.001 |
 High | 1340 (51%) | 1289 (49%) |  |
Histologic grade initial primary breast tumor | |||
 Low/Intermediate | 583 (29%) | 1447 (71%) | <.001 |
 High | 1943 (44%) | 2498 (56%) |  |
 Tumor size (mean, range, F statistic) | 2.91 (.10, 18.00) | 1.51 (.05, 17.00) | <.001 |
 # Positive nodes (mean, range, F statistic) | 1.67 (0–44) | .57 (0–35) | <.001 |
Treatment | |||
 Surgery only | 339 (36%) | 614 (64%) | <.001 |
 Surgery/radiation | 575 (22%) | 1997 (78%) |  |
 Surgery/chemotherapy | 412 (53%) | 372 (47%) |  |
 Surgery/radiation/chemotherapy | 1240 (54%) | 1054 (46%) |  |
Distant recurrence | |||
 Yes | 289 (68%) | 133 (32%) | <.001 |