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Table 1 Summary of targeted biomarkers and their relative expression levels in breast (MCF7, 4175TR) and ovarian (SKOV3) cancer cell lines. Also listed are the corresponding targeting ligands and nanoparticle compositions

From: Shortwave infrared emitting multicolored nanoprobes for biomarker-specific cancer imaging in vivo

  Biomarker
CAV1 CXCR4 FRα
MCF7 expression + +++ ++
4175TR expression +++ +
SKOV3 expression +++ +++
Targeting ligand Daidzein AMD3100 Folic acid
Visible / SWIR reporter Rhodamine / Ho FITC / Er Alexa Fluor 647 / Tm
Targeted nanoparticle Rh-fHoANC FITC-fErANC 647-fTmANC
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