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Table 1 Demographic characteristics of primary LC patients with or without t-AML

From: Clinicopathological features, risk and survival in lung cancer survivors with therapy-related acute myeloid leukaemia

Variables, No. (%)

With t-AML

(N = 104)

Without t-AML

(N = 158,541)

P

Sex

  

0.087

 Male

52 (50)

92,390 (58.3)

 

 Female

52 (50)

66,151 (41.7)

 

Race

  

0.999

 White

86 (82.7)

130,695 (82.4)

 

 Black

11 (10.6)

16,891 (10.7)

 

 Other

7 (6.7)

10,824 (6.8)

 

Age of LC diagnosis, median (range)

62.5 (41–82)

64 (10–100)

0.332

 < 65 years

58 (55.8)

80,876 (51.0)

 

 ≥ 65 years

46 (44.2)

77,665 (49.0)

 

Period of diagnosis

  

0.131

 1975–1984

7 (6.7)

22,500 (14.2)

 

 1985–1994

12 (11.5)

33,044 (20.8)

 

 1995–2004

29 (27.9)

45,654 (28.8)

 

 2005–2015

56 (53.8)

57,342 (36.2)

 

Surgical treatment

  

0.006

 Yes

22 (21.2)

19,395 (12.2)

 

 No

82 (78.8)

139,146 (87.8)

 

Radiation treatment

  

0.001

 Yes

78 (75.0)

92,389 (58.3)

 

 No/unknown

26 (25.0)

66,152 (41.7)

 

Stage

  

< 0.001

 Localized/regional

53 (51.0)

41,086 (25.9)

 

 Distant

39 (37.5)

81,744 (52.2)

 

 Unknown

12 (11.5)

34,711 (21.9)

 

Pathologic grade

  

0.659

 I or II

13 (12.5)

16,116 (10.2)

 

 III or IV

39 (37.5)

64,510 (40.7)

 

 Unknown

52 (50.0)

77,915 (49.1)

 

Histologic type

  

0.09

 SCLC

42 (40.4)

51,078 (32.2)

 

 NSCLC

59 (56.7)

96,664 (61.0)

 

 Unknown

3 (2.9)

10,799 (6.8)

 
  1. LC Lung cancer, t-AML Therapy-related acute myeloid leukaemia, NSCLC Non-small cell lung cancer, SCLC Small cell lung cancer, SEER Surveillance, Epidemiology, and End Results