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Table 3 Factors associated with loss of follow-up in the first 3 years after surgery (N = 420)

From: Adherence to post-surgery follow-up assessment and its association with sociodemographic and disease characteristics in patients with breast cancer in Central China

Characteristic Unadjusted OR (95% CI) Adjusted OR (95% CI) *
Age(years)
  < 65 1.0 1.0
  > 65 5.70 (3.28–9.92) 2.31 (1.13–4.73)
Medical insurance coverage
 High (> 70%) 1.0 1.0
 Medium (50–70%) 2.36 (1.28–4.36) 3.21 (1.53–6.73)
 Low (< 50%) 2.86 (1.44–5.66) 3.58 (1.57–8.15)
Family history
 Negative 1.0  
 Positive 1.24 (0.47–3.24)  
Marital status
 Married 1.0  
 Unmarried 2.20 (0.93–5.19)  
Employment status
 Employed 1.0  
 Unemployed 1.15 (0.58–2.28)  
 Retired 0.77 (0.42–1.41)  
Tumor size (cm)
 0–1.9 1.0  
 2–4.9 1.28 (0.79–2.09)  
  > 5 2.44 (0.89–6.68)  
Positive axillary nodal status
 0 1.0  
 1–3 1.15 (0.68–1.94)  
 4–9 1.74 (0.82–3.69)  
  > 10 1.47 (0.55–3.96)  
TNM stage
 Stage 0-I 1.0  
 Stage II 1.17 (0.70–1.95)  
 Stage III 1.44 (0.73–2.83)  
Histological subtype
 In Situ 1.0  
 Ductal/Lobular/Mixed/Metaplastic 0.49 (0.11–2.08)  
 Tubular/Mucinous/Papillary 0.13 (0.01–1.54)  
ER
 Negative 1.0  
 Positive 1.32 (0.79–2.20)  
PR
 Negative 1.0  
 Positive 1.24 (0.76–2.01)  
HER2
 Negative 1.0  
 Positive 0.84 (0.47–1.52)  
Surgery of breast
 Lumpectomy 1.0  
 Mastectomy 1.37 (0.86–2.18)  
Axillary surgery
 Sentinel lymph node biopsy 1.0 1.0
 Axillary lymph node dissection 1.57 (0.97–2.53) 2.51 (1.39–4.52)
Chemotherapy
 Yes 1.0 1.0
 No 5.27 (3.19–8.70) 3.48 (1.84–6.57)
Radiotherapy
 Yes 1.0 1.0
 No 5.32 (3.25–8.71) 3.90 (2.14–7.10)
Targeted therapy
 Yes 1.0  
 No 3.24 (1.13–9.28)  
Endocrine therapy
 Yes 1.0  
 No 1.65 (1.03–2.64)  
  1. Abbreviations: ER Estrogen receptor status, PR Progesterone receptor status, HER 2 Human epidermal growth factor receptor 2
  2. *Adjusted ORs in the final model from step-wise logistic regression analysis by including all the variables in the Table with P < 0.10 from univariate logistic regression and eliminate each at a time justified by likelihood ratio test [13]
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