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Table 8 Clinicopathological findings of GI-NEN cases in which MGMT promoter methylation status was analyzed using methylation-specific PCR

From: O6-methylguanine DNA methyltransferase and glucose transporter 2 in foregut and hindgut gastrointestinal neuroendocrine neoplasms

Case No.a Primary site Grade Ki-67 labeling index MGMT score H-score MGMT methylation-specific PCR
1 rectum NET G2 6.83572 1 3.65854 negative
2 stomach NET G2 10.9264 2 182.374 negative
3 rectum NET G2 3.73832 3 271.554 negative
4 rectum NET G1 1.17057 3 257.354 negative
5 rectum NET G1 1.38648 3 207.671 negative
6 duodenum NET G1 0.874317 3 232.395 negative
7 rectum NET G1 0.334076 3 175.391 negative
8 duodenum NET G2 5.42636 3 291.156 negative
9 rectum NET G1 0.475436 3 246.119 negative
10 duodenum NET G2 3.52588 3 176.573 negative
11 duodenum NET G1 2 3 240.253 negative
12 duodenum NET G1 1.97239 3 275.166 negative
13 rectum NET G1 1.33038 3 298.588 negative
14 rectum NET G1 0.740741 3 270.837 negative
15 rectum NET G1 1.37741 3 243.583 negative
16 rectum NET G2 11.9792 3 204.144 negative
17 duodenum NET G1 2.89389 2 111.254 negative
18 rectum NET G1 0.788955 3 243.867 negative
19 duodenum NET G2 12.8111 2 282.641 negative
20 rectum NET G1 1.44778 3 298.456 negative
21 duodenum NET G1 1.0043 3 227.732 negative
22 rectum NET G2 3.78007 3 288.949 negative
23 rectum NET G1 0.797101 3 248.495 negative
24 stomach NET G2 3.10786 3 260.254 negative
25 rectum NET G1 2.23842 3 254.59 negative
26 rectum NET G1 1.46036 3 268.528 negative
27 rectum NET G1 1.27907 3 232.112 negative
28 stomach NET G1 1.86757 3 217.736 negative
29 stomach NET G2 3.7929 1 67.3792 negative
30 stomach NET G1 1.60494 3 296.608 negative
31 rectum NET G1 2.55924 2 191.369 negative
32 rectum NET G1 0.840925 3 257.453 negative
33 duodenum NET G1 1.90476 2 117.661 negative
34 rectum NET G2 7.36722 2 141.194 negative
35 duodenum NET G1 0.623539 1 158.554 negative
36 EG junction NEC 96.223 3 223.134 negative
37 stomach NEC 99.1404 2 193.032 negative
38 sigmoid colon NEC 92.9985 0 0 positive
39 esophagus NEC 74.7155 3 217.818 negative
40 stomach NEC 99.7234 3 246.952 negative
41 esophagus NEC 100 3 243.81 negative
42 stomach NEC 77.2152 2 205.957 negative
43 stomach NEC 85.7143 3 250.857 negative
44 stomach NEC 79.533 2 166.723 negative
45 esophagus NEC 99.2844 3 119.098 negative
46 rectum NEC 95.1153 3 146.898 negative
47 rectum NEC 88.974 2 212.279 negative
48 sigmoid colon NEC 98.7198 3 155.372 positive
49 duodenum NEC 98.7441 3 225.577 negative
  1. aPatient characteristics of these cases: male, n = 32; female, n = 17/ Median age in years (range), 66 (39–86)