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Table 1 Summary of results and clinicopathological characteristics of GI-NEN cases examined in this study

From: O6-methylguanine DNA methyltransferase and glucose transporter 2 in foregut and hindgut gastrointestinal neuroendocrine neoplasms

Patient characteristics of neuroendocrine tumor

 Total number

70

 Sex, male/female

42/28

 Median age in years (range)

60 (33–82)

 Grade (WHO 2019)

NET-G1, n = 49; NET-G2, n = 19; NET-G3, n = 2

 Primary lesion of NET

Foregut, n = 33; Hindgut, n = 37

 Case of lymph node metastasis in NET G1

Metastatic (pathologically), n = 5; Not detected (clinically), n = 20;Not detected (pathologically), n = 10; Unclarified, n = 14

 MGMT score

Score0, n = 1; Score1, n = 15; Score2, n = 15; Score3, n = 39

 GLUT2 score

Score0, n = 21; Score1, n = 10; Score2, n = 18; Score4, n = 18; Score6, n = 3

 MGMT methylation specific PCR

Negative, n = 35; Positive, n = 0; Not examined, n = 35

 Median Ki-67 labeling indexa (range)

1.89 (0.33–48.3)

Patient characteristics of neuroendocrine carcinoma

 Total number

14

 Sex, male/female

10/4

 Median age in years (range)

70 (60–86)

 Primary lesion of NEC

Foregut, n = 10; Hindgut, n = 4

 MGMT score

Score0, n = 1; Score1, n = 0; Score2, n = 4; Score3, n = 9

 MGMT methylation specific PCR

Negative, n = 12; Positive, n = 2

  1. aRound the fourth digit