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Table 1 Baseline Characteristics of Patients with Gallbladder Carcinoma from the SEER and Multicenter Database

From: Modification of the 8th American Joint Committee on Cancer staging system for gallbladder carcinoma to improve prognostic precision

Variables Frequency (%)
SEER (2779) Multicenter (591)
Age
 < 65 1130 (40.7%) 314 (53.1%)
 ≥ 65 1649 (59.4%) 277 (46.9%)
Sex
 Male 835 (30.0%) 209 (35.4%)
 Female 1944 (70.0%) 382 (64.6%)
Race
 White 2100 (75.6%) 0
 Black 348 (12.5%) 0
 Others 331 (11.9%) 591 (100%)
Vital Status
 Dead 1724 (62.0%) 436 (73.8%)
 Alive 1055 (38%) 155 (26.2%)
Grade
 Well/moderate 1525 (54.9%) 360 (60.9%)
 Poor/undifferentiated 1038 (37.3%) 231 (39.1%)
 Unknown 216 (7.8%) 0
T category(8th)
 T1 377 (13.6%) 91 (15.4%)
 T2 1187 (42.7%) 264 (44.7%)
 T3 1083 (39.0%) 210 (35.5%)
 T4 132 (4.7%) 26 (4.4%)
N category(8th)
 N0 1381 (49.7%) 337 (57.0%)
 N1 1258 (45.3%) 219 (37.1%)
 N2 140 (5.0%) 35 (5.9%)
 Median (range) 1 (0–22) 2 (0–9)
No. of LN evaluationa
 < 6 2130 (78.8%) 413 (69.9%)
 ≥ 6 573 (21.2%) 178 (30.1%)
 Median (range) 2 (1–40) 2 (1–24)
M category(8th)
 M0 2290 (82.4%) 483 (81.7%)
 M1 489 (17.6%) 108 (18.3%)
TNM Stage(8th)
 I 298 (10.7%) 57 (9.6%)
 II 592 (21.3%) 149 (25.2%)
 IIIA 326 (11.7%) 62 (10.5%)
 IIIB 897 (32.3%) 174 (29.4%)
 IVA 80 (2.9%) 18 (3.0%)
 IVB 586 (21.1%) 132 (22.3%)
Chemotherapy
 Yes 1183 (42.6%) 317 (53.6%)
 No/unknown 1596 (57.4%) 274 (46.4%)
Radiotherapy
 Yes 723 (26.0%) 184 (31.1%)
 No 2056 (74.0%) 407 (68.9%)
  1. a76 cases missing in the SEER database