Table 6 Major case series since 2000 of multimodal treated central neurocytomas (N < 10). Note the different treatment options and outcome findings
Study | Patients | Treatments | Complete removal | Outcome | Mortality |
|---|---|---|---|---|---|
Sharma et al. [74] | 20 | GTR 70.0% (14) + RT STR 30.0% (6) + RT | 70.0% (14) | 15/20 OS: 66.7% | 25% |
Leenstra et al. [75] | 45 | GTR (15) STR (14) GTR/RT (4) STR/RT (7) GTR/RT/CH (2) STR/RT/CH (1) Bx/RT (2) | 46.6% (21) | 10y OS: 83.0% 10y LC: 60.0% | n.m. |
Hallock et al. [76] | 20 | GTR (10) STR (8) STR/RT (1) No treatment (1) | 50.0% (10) | 10y OS: 82.0% 10y LC: 61.0% | n.m. |
Imber et al. [72] | 28 | GTR (8) STR (16) GTR/EBRT (1) STR/RT (3) | 32.1% (9) | 5y PFS: 40.0% 5y PFS: 53.0% n.m. 5y PFS: 67.0% | 5y OS: 96.0%, 10y OS: 82.0% |
Aftahy et al. (present series) | 10 | GTR (9) STR (1) | 90.0% (9/10) | 2y OS: 100% | 0% |