Fig. 5From: A bispecific T cell engager targeting Glypican-1 redirects T cell cytolytic activity to kill prostate cancer cellsT cell inflammatory cytokine release in response to specific MIL-38-CD3 BiTE activation. Purified T cells were cultured with DU-145 cells in the presence of varying concentrations of MIL-38-CD3 or equivalent concentration of non-targeted control BiTE CD3-PEG for 72 h. Supernatants were collected and assayed for IFN-γ (a) and TNF (b) ****p < 0.0001; ***p < 0.001Back to article page