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Table 2 Univariate and Multivariate Analyses for OS

From: Nutritional and inflammatory measures predict survival of patients with stage IV colorectal cancer

Variable Category Reference Univariate Multivariatea
HR (95% CI) p value HR (95% CI) p value
CONUT score Intermediate (2/3) Low (0/1) 1.27 (1.08–1.49) 0.004 1.20 (1.02–1.42) 0.032
  High (≥4) Low (0/1) 1.84 (1.45–2.31) < 0.001 1.57 (1.23–1.98) < 0.001
  High (≥4) Intermediate (2/3) 1.45 (1.13–1.86) 0.005 1.30 (1.01–1.67) 0.045
PNI Low (< 48.0) High (≥48.0) 1.62 (1.40–1.87) < 0.001 1.39 (1.19–1.62) < 0.001
mGPS 1 0 2.26 (1.90–2.67) < 0.001 1.84 (1.54–2.19) < 0.001
  2 0 2.83 (2.28–3.47) < 0.001 2.06 (1.65–2.55) < 0.001
  2 1 1.25 (0.99–1.58) 0.063 1.12 (0.88–1.41) 0.349
  1. a Adjusted for the following variables: age, gender, BMI, ECOG performance status,
  2. location of primary tumor, CEA levels, histological type, M category, and surgical treatment
  3. Data are presented as hazard ratios and 95% confidence intervals
  4. HR Hazard ratio, CI Confidence interval, CONUT Controlling nutritional status
  5. PNI Prognostic nutritional index, mGPS Modified Glasgow prognostic score
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