Fig. 4

Verteporfin induces cell apoptosis in three different molecular subtypes of BC cells. BC cells were supplemented using the vehicle control or verteporfin and labelled with TUNEL. Data were presented as mean ± SD, *P < 0.05, **P < 0.01, ***P < 0.001 (a). BC cells were treated using different concentrations of verteporfin for 72 h, and subjected to western blotting analysis to determine the levels of the YAP target Survivin (b), BAX and Bcl-2 levels (c), and PARP, cleaved PARP, Caspase-9 and cleaved Caspase-9 expressions, full-length blots are presented in Supplementary Figure 4d (d)