|
Variables
|
Training cohort(N = 10,340)
|
Validation cohort(N = 4432)
|
P value
|
|---|
|
Without BM(N = 10,268)
|
With BM(N = 72)
|
Without BM(N = 4384)
|
With BM(N = 48)
|
|---|
|
Age (years)
|
0.757
|
|
<50
|
5430 (52.9%)
|
10 (13.9%)
|
2333 (53.2%)
|
11 (2.3%)
|
|
≥ 50
|
4838 (47.1%)
|
62 (86.1%)
|
2051 (46.8%)
|
37 (97.7%)
|
|
Race
|
0.790
|
|
Black
|
751 (7.3%)
|
16 (22.2%)
|
334 (7.6%)
|
7 (14.6%)
|
|
Other a
|
1262 (12.3%)
|
7 (9.7%)
|
528 (12.0%)
|
5 (10.4%)
|
|
White
|
8255 (80.4%)
|
49 (68.1%)
|
3522 (80.4%)
|
36 (75.0%)
|
|
Sex
|
0.743
|
|
Female
|
7802 (76.0%)
|
39 (54.2%)
|
3348 (76.4%)
|
24 (50.0%)
|
|
Male
|
2466 (24.0%)
|
33 (45.8%)
|
1036 (23.6%)
|
24 (50.0%)
|
|
Histology
|
0.368
|
|
ATC
|
203 (2.0%)
|
24 (33.3%)
|
68 (1.6%)
|
11 (22.9%)
|
|
FTC
|
642 (6.3%)
|
16 (22.2%)
|
272 (6.2%)
|
13 (27.1%)
|
|
MTC
|
82 (0.8%)
|
2 (2.8%)
|
30 (0.7%)
|
1 (2.1%)
|
|
PTC
|
9341 (91.0%)
|
30 (41.7%)
|
4014 (91.5%)
|
23 (47.9%)
|
|
Grade
|
0.092
|
|
Grade I
|
8247 (80.3%)
|
19 (26.3%)
|
3525 (80.4%)
|
21 (43.8%)
|
|
Grade II
|
1462 (14.2%)
|
12 (16.7%)
|
636 (14.5%)
|
5 (10.4%)
|
|
Grade III
|
272 (2.6%)
|
10 (13.9%)
|
129 (2.9%)
|
9 (18.8%)
|
|
Grade IV
|
287 (2.8%)
|
31 (43.1%)
|
94 (2.2%)
|
13 (27.0%)
|
|
Laterality
|
0.806
|
|
Unilateral
|
10,201 (99.3%)
|
70 (97.2%)
|
4356 (99.4%)
|
48 (100.0%)
|
|
Bilateral
|
67 (0.7%)
|
2 (2.8%)
|
28 (0.6%)
|
0 (0.0%)
|
|
T stage
|
0.317
|
|
T1
|
5740 (55.9%)
|
4 (5.5%)
|
2460 (56.1%)
|
10 (20.8%)
|
|
T2
|
1789 (17.4%)
|
8 (11.1%)
|
795 (18.1%)
|
6 (12.5%)
|
|
T3
|
2165 (21.1%)
|
21 (29.2%)
|
916 (20.9%)
|
12 (25.0%)
|
|
T4
|
574 (5.6%)
|
39 (54.2%)
|
213 (4.9%)
|
20 (41.7%)
|
|
N Stage
|
0.252
|
|
N0
|
7650 (74.5%)
|
35 (48.6%)
|
3231 (73.7%)
|
23 (47.9%)
|
|
N1
|
2618 (25.5%)
|
37 (51.4%)
|
1153 (26.3%)
|
25 (52.1%)
|
|
Tumor size
|
0.569
|
|
<2 cm
|
6216 (60.5%)
|
8 (11.1%)
|
2643 (60.3%)
|
12 (25.0%)
|
|
2–4 cm
|
1244 (12.1%)
|
45 (62.5%)
|
505 (11.5%)
|
28 (58.3%)
|
|
>4 cm
|
2808 (27.3%)
|
19 (26.4%)
|
1236 (28.2%)
|
8 (16.7%)
|
|
Insurance status
|
0.924
|
|
Insured
|
10,019 (97.6%)
|
71 (98.6%)
|
4280 (97.6%)
|
46 (95.8%)
|
|
Uninsured
|
249 (2.4%)
|
1 (1.4%)
|
104 (2.4%)
|
2 (4.2%)
|
|
Marital status
|
0.927
|
|
Married
|
6606 (64.3%)
|
42 (58.3%)
|
2821 (64.3%)
|
32 (66.7%)
|
|
Unmarried
|
3662 (35.7%)
|
30 (41.7%)
|
1563 (35.7%)
|
16 (33.3%)
|
- Data notes: a Includes: American Indian, native Alaskan and Asian, Pacific Islander; PTC papillary thyroid carcinoma, FTC Follicular thyroid carcinoma, ATC Anaplastic thyroid carcinoma, MTC Medullary thyroid carcinoma
