|
Variable
|
Univariate analysis
|
Multivariable analysis
|
|---|
|
HR (95% CI)
|
P
|
HR (95% CI)
|
P
|
|---|
|
NTRS Group
|
3.01 (2.39-3.81)
|
< 0.001***
|
1.50 (1.14-1.98)
|
< 0.01**
|
|
Age
|
1.74 (1.39-2.19)
|
< 0.001***
|
/
|
/
|
|
Gender
|
0.95 (0.76-1.19)
|
0.67
|
/
|
/
|
|
Histology
|
1.51 (1.34-1.71)
|
< 0.001***
|
0.80 (0.69-0.93)
|
< 0.01**
|
|
Grade
|
2.81 (2.38-3.30)
|
< 0.001***
|
2.75 (2.13-3.55)
|
< 0.001***
|
|
IDH.status
|
0.32 (0.25-0.40)
|
< 0.001***
|
0.70 (0.53-0.92)
|
< 0.01**
|
|
Chr.1p/19q.codeletion
|
0.28 (0.20-0.39)
|
< 0.001***
|
0.55 (0.37-0.82)
|
< 0.01**
|
- NTRS (low and high); Gender (female and male); Histology (astrocytoma, oligodendroglioma, oligoastrocytoma and glioblastoma); Grade (II, III and IV); IDH status (wildtype and mutant); 1p/19q (non-codeletion and codeletion); P < 0.05 (*), P < 0.01 (**) and P < 0.001 (***) is regarded as statistically significant
- HR hazard ratio, CI confidence interval
